Table 2 Multivariable analysis using the Gompertz Cox-Regression model for predictor’s vascular complication among type 2 DM patients in university of Gondar referral hospital September, 2005 – March 2017
Variable | Crud HR (95% CI) | Adjusted HR (95% CI) |
|---|---|---|
Age(year) | 1.04(1.03, 1.06) | 1.02 (0.99, 1.04) |
Sex | ||
 Female | 1 | 1 |
 Male | 0.47(0.31, 0.73) | 0.50(0.27, 0.94)* |
Residence | ||
 Rural | 1 | 1 |
 Urban | 1.47(0.84, 2.60) | 0.51(0.25, 1.02) |
Occupation | ||
 Unemployed | 1 | 1 |
 Government | 0.80(0.41,1.57) | 0.796(0.41, 1.56) |
 NGO | 0.38(0.14,1.05) | 0.85 (0.27, 2.70) |
 Private | 0.52(0.31,0.88) | 0.83 (0.39, 1.74) |
Family history | ||
 Yes | 1 | 1 |
 NO | 2.17(1.45, 3.23) | 1.25 (0.78, 2.01) |
Treatment Type | ||
 OHA | 1 | 1 |
 Insulin | 0.79(0.45, 1.36) | 0.50(0.28, 1.01) |
 Insulin + OHA | 0.87(0.46, 1.67) | 0.91(0.48, 1.72) |
BMI kg/m2 | ||
 18.5–24.99 | 1 | 1 |
  < 18.5 | 0.82(0.32, 2.10) | 1.07(0.34, 3.27) |
 25–29.9 | 2.04(1.27, 3.29) | 0.66(0.37, 1.16) |
  ≥ 30 | 4.22(2.47, 7.21) | 0.84(0.44, 1.61) |
Hypertension | ||
 No | 1 | 1 |
 Yes | 10.57(5.48, 20.38) | 3.99(1.87, 8.56)*** |
SBP(mm Hg) | 1.03(1.0, 1.04) | 0.995(0.97, 1.01) |
DBP(mm Hg) | 1.07(1.05, 1.09) | 1.02(0.99, 1.05) |
HDL-C(mg/dl) | ||
  < 40 | 1 | 1 |
  ≥ 40 | 0.12(0.07, 0.18) | 0.43(0.24, 0.77)** |
LDL-C(mg/dl) | ||
  ≤ 100 | 1 | 1 |
  > 100 | 13.12(7.14,24.10) | 3.05(1.47, 6.35)** |
Cholesterol (mg/dl) | ||
  ≤ 200 | 1 | 1 |
  > 200 | 4.67(2.99, 7.28) | 0.76(0.43, 1.36) |
Triglyceride(mg/dl) | ||
  ≤ 150 | 1 | 1 |
  > 150 | 8.08(4.50, 14.49) | 2.74(1.28, 5.84)** |
FBS(mg/dl) | 1.008(1.006,1.010) | 1.00(0.999,1.005) |
Creatinine(mg/dl) | 1.003(0.995,1.010) | 100(0.995, 1.009) |
Protein urea | ||
 Negative | 1 | 1 |
 Positive | 4.14(2.77, 6.19) | 1.69(1.03, 2.78)* |