Table 2 The biochemical results of the single-dose and daily-dosage group at pretreatment, 4th, and 12th week
| Â | Single-dose group | Daily-dosage group | ||||||
|---|---|---|---|---|---|---|---|---|
Pretreatment | 4th week | 12th week | p | Pretreatment | 4th week | 12th week | p | |
Glucose (mg/dL) | 88.2 ± 9.8 | 81.7 ± 17.4 | 92.4 ± 9.5 | 0.014 | 89.1 ± 7.5 | 85.3 ± 6.8 | 88.6 ± 18.0 | 0.016 |
Total cholesterol (mg/dL) | 209.5 ± 37.4 | 209.1 ± 27.0 | 204.7 ± 35.4 | 0.569 | 203.6 ± 36.6 | 1999.1 ± 38.8 | 212.3 ± 33.6 | 0.763 |
Triglycerides (mg/dL) | 136.5 ± 49.6 | 115.6 ± 43.7 | 128.7 ± 56.1 | 0.108 | 148.5 ± 72.7 | 146.6 ± 90.3 | 154.6 ± 61.9 | 0.601 |
LDL-cholesterol (mg/dL) | 133.4 ± 32.3 | 137.5 ± 23.7 | 131.3 ± 26.7 | 0.411 | 125.6 ± 27.8 | 122.1 ± 31.1 | 134.5 ± 32.2 | 0.301 |
Calcium | ||||||||
 (mg/dL) | 9.5 ± 0.4 | 9.5 ± 0.4 | 9.4 ± 0.5 | 0.507 | 9.4 ± 0.4 | 9.5 ± 0.5 | 9.6 ± 0.4 | 0.059 |
 (mmol/L) | 2.3 ± 0.1 | 2.3 ± 0.1 | 2.3 ± 0.1 |  | 2.3 ± 0.1 | 2.3 ± 0.1 | 2.4 ± 0.1 |  |
Phosphorus (mg/dL) | 3.5 ± 0.4 | 3.8 ± 0.4 | 3.6 ± 0.6 | 0.043 | 3.4 ± 0.5 | 3.9 ± 0.5 | 3.9 ± 0.5 | < 0.001 |
Magnesium (mg/dL) | 2.1 ± 0.2 |  |  |  | 2.2 ± 0.2 |  |  |  |
iPTH (pg/ml) | 55.1 ± 24.3 | 47.7 ± 19.1 | 50.7 ± 20.5 | 0.152 | 62.4 ± 24.9 | 55.9 ± 22.8 | 54.9 ± 20.6 | 0.081 |
Vitamin D | ||||||||
 (ng/mL) | 9.7 ± 4.4 | 35.9 ± 9.6 | 23.1 ± 4.7 | < 0.001 | 10.2 ± 4.4 | 16.9 ± 5.8 | 19.8 ± 7.2 | < 0.001 |
 (nmol/L) | 24.2 ± 10.9 | 89.6 ± 23.9 | 57.6 ± 11.7 |  | 25.4 ± 10.9 | 42.1 ± 14.4 | 49.4 ± 17.9 |  |
Osteocalcin (ng/ml) | 21.2 ± 19.1 | 21.9 ± 7.5 | 20.5 ± 7.6 | 0.231 | 11.2 ± 8.3 | 22.0 ± 7.2 | 20.4 ± 5.5 | 0.008 |
Alkaline phosphatase (units/L) | 72.5 ± 20.7 | 73.0 ± 23.1 | 73.6 ± 19.8 | 0.138 | 69.6 ± 17.6 | 68.1 ± 19.6 | 68.0 ± 19.1 | 0.051 |
TSH (mIU/L) | 2.5 ± 1.5 | 2.8 ± 2.0 | 2.4 ± 1.5 | 0.580 | 2.2 ± 1.1 | 2.2 ± 1.3 | 2.2 ± 1.4 | 0.965 |
hs-CRP (mg/L) | 3.3 ± 3.1 | 3.2 ± 3.2 | 2.4 ± 2.2 | 0.188 | 4.5 ± 4.9 | 4.1 ± 3.7 | 4.1 ± 3.9 | 0.376 |