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Table 2 The biochemical results of the single-dose and daily-dosage group at pretreatment, 4th, and 12th week

From: The effects of single high-dose or daily low-dosage oral colecalciferol treatment on vitamin D levels and muscle strength in postmenopausal women

  Single-dose group Daily-dosage group
Pretreatment 4th week 12th week p Pretreatment 4th week 12th week p
Glucose (mg/dL) 88.2 ± 9.8 81.7 ± 17.4 92.4 ± 9.5 0.014 89.1 ± 7.5 85.3 ± 6.8 88.6 ± 18.0 0.016
Total cholesterol (mg/dL) 209.5 ± 37.4 209.1 ± 27.0 204.7 ± 35.4 0.569 203.6 ± 36.6 1999.1 ± 38.8 212.3 ± 33.6 0.763
Triglycerides (mg/dL) 136.5 ± 49.6 115.6 ± 43.7 128.7 ± 56.1 0.108 148.5 ± 72.7 146.6 ± 90.3 154.6 ± 61.9 0.601
LDL-cholesterol (mg/dL) 133.4 ± 32.3 137.5 ± 23.7 131.3 ± 26.7 0.411 125.6 ± 27.8 122.1 ± 31.1 134.5 ± 32.2 0.301
Calcium
 (mg/dL) 9.5 ± 0.4 9.5 ± 0.4 9.4 ± 0.5 0.507 9.4 ± 0.4 9.5 ± 0.5 9.6 ± 0.4 0.059
 (mmol/L) 2.3 ± 0.1 2.3 ± 0.1 2.3 ± 0.1   2.3 ± 0.1 2.3 ± 0.1 2.4 ± 0.1  
Phosphorus (mg/dL) 3.5 ± 0.4 3.8 ± 0.4 3.6 ± 0.6 0.043 3.4 ± 0.5 3.9 ± 0.5 3.9 ± 0.5 < 0.001
Magnesium (mg/dL) 2.1 ± 0.2     2.2 ± 0.2    
iPTH (pg/ml) 55.1 ± 24.3 47.7 ± 19.1 50.7 ± 20.5 0.152 62.4 ± 24.9 55.9 ± 22.8 54.9 ± 20.6 0.081
Vitamin D
 (ng/mL) 9.7 ± 4.4 35.9 ± 9.6 23.1 ± 4.7 < 0.001 10.2 ± 4.4 16.9 ± 5.8 19.8 ± 7.2 < 0.001
 (nmol/L) 24.2 ± 10.9 89.6 ± 23.9 57.6 ± 11.7   25.4 ± 10.9 42.1 ± 14.4 49.4 ± 17.9  
Osteocalcin (ng/ml) 21.2 ± 19.1 21.9 ± 7.5 20.5 ± 7.6 0.231 11.2 ± 8.3 22.0 ± 7.2 20.4 ± 5.5 0.008
Alkaline phosphatase (units/L) 72.5 ± 20.7 73.0 ± 23.1 73.6 ± 19.8 0.138 69.6 ± 17.6 68.1 ± 19.6 68.0 ± 19.1 0.051
TSH (mIU/L) 2.5 ± 1.5 2.8 ± 2.0 2.4 ± 1.5 0.580 2.2 ± 1.1 2.2 ± 1.3 2.2 ± 1.4 0.965
hs-CRP (mg/L) 3.3 ± 3.1 3.2 ± 3.2 2.4 ± 2.2 0.188 4.5 ± 4.9 4.1 ± 3.7 4.1 ± 3.9 0.376