Table 2 Baseline Characteristics of IMS III Subjects and by Obesity Categories and Diabetes Status
Characteristic | All subjects | No Diabetes | Diabetes | ||
|---|---|---|---|---|---|
| Â | Â | Non-Obese | Obese | Non-Obese | Obese |
| Â | No. (%) | No. (%) | No. (%) | No. (%) | No. (%) |
No. of subjects a | 645 | 398 | 101 | 81 | 65 |
Obese | |||||
 Yes | 166 (25.74) |  |  |  |  |
 No | 479 (74.26) |  |  |  |  |
Diabetes | |||||
 Yes | 146 (22.64) |  |  |  |  |
 No | 499 (77.36) |  |  |  |  |
Sociodemographic Characteristics | |||||
 Age | |||||
   > 65 years | 377 (58.45) | 230 (57.79) | 48 (47.52) | 64 (79.01) | 35 (53.85) |
 Gender | |||||
  Male | 334 (51.78) | 222 (55.78) | 37 (36.63) | 37 (45.68) | 38 (58.46) |
 Race/ethnicity | |||||
  White | 545 (84.50) | 339 (85.18) | 87 (86.14) | 61 (75.31) | 58 (89.23) |
  Black/Other | 100 (15.50) | 59 (14.82) | 14 (13.86) | 20 (24.69) | 7 (10.77) |
Clinical Characteristics | |||||
 Qualifying stroke subtype | |||||
  Large vessel atherosclerosis | 127 (19.69) | 70 (17.59) | 24 (23.76) | 18 (22.22) | 15 (23.08) |
  Cardioembolic | 299 (46.36) | 185 (46.48) | 46 (45.54) | 37 (45.68) | 31 (47.69) |
  Small vessel disease/Other/Unknown | 219 (33.95) | 143 (35.93) | 31 (30.69) | 26 (32.10) | 19 (29.23) |
 Baseline stroke severity | |||||
  Severe (NIHSS ≥20) | 198 (30.99) | 6.3 (5.6-7.5) | 6.7 (5.9-7.4) | 8.2 (6.2-10.0) | 8.8 (6.9-12.5) |
 Baseline glucose (median, IQR) | 6.7 (5.7-8.1) | 6.3 (5.6-7.4) | 6.7 (5.9-7.4) | 8.2 (6.1-10.0) | 8.8 (6.9-12.3) |
 Baseline systolic blood pressure | |||||
   ≥ 140 mmHg | 386 (60.60) | 219 (55.73) | 67 (67.68) | 62 (77.50) | 38 (58.46) |
 Baseline diastolic blood pressure (median, IQR) | 81 (71-94) | 80 (70-93) | 85 (70.5-98) | 85 (73-96) | 80 (71-91) |
 Treatment assignment | |||||
  IV rt-PA+ Endovascular therapy | 429 (66.51) | 274 (68.84) | 61 (60.40) | 50 (61.73) | 44 (67.69) |
  IV rt-PA | 216 (33.49) | 124 (31.16) | 40 (39.60) | 31 (38.27) | 21 (32.31) |
Risk Factors and Comorbidities | |||||
 Smoking status | |||||
  Current smoker | 160 (24.81) | 106 (26.63) | 30 (29.70) | 14 (17.28) | 10 (15.38) |
 Alcohol use | |||||
  Current drinker | 251 (38.91) | 165 (41.46) | 43 (42.57) | 21 (25.93) | 22 (33.85) |
 History of a previous stroke | |||||
  Yes | 86 (13.33) | 46 (11.56) | 9 (8.91) | 21 (25.93) | 10 (15.38) |
 History of hypertension | |||||
  Yes | 482 (74.73) | 269 (67.59) | 79 (78.22) | 72 (88.89) | 62 (95.38) |
 History of coronary artery disease | |||||
  Yes | 170 (26.36) | 90 (22.61) | 22 (21.78) | 37 (45.68) | 21 (32.31) |
 History of atrial fibrillation | |||||
  Yes | 192 (29.77) | 120 (30.15) | 30 (29.70) | 22 (27.16) | 20 (30.77) |