Skip to main content

Table 3 Adjusted changes in metabolic profile of the patients with polycystic ovary syndrome

From: The effects of synbiotic supplementation on hormonal status, biomarkers of inflammation and oxidative stress in subjects with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial

  Placebo group (n = 30) Synbiotic group (n = 30) pa
Total testosterone (ng/mL) − 0.2 ± 0.1 − 0.3 ± 0.1 0.26
SHBG (nmol/L) 0.7 ± 6.1 19.5 ± 6.1 0.03
FAI −0.04 ± 0.02 −0.10 ± 0.02 0.04
mF-G scores −0.1 ± 0.3 −1.3 ± 0.3 0.007
DHEAS (μg/mL) −0.1 ± 0.1 −0.3 ± 0.1 0.18
hs-CRP (ng/mL) 375.6 ± 339.8 −990.2 ± 339.8 0.006
NO (μmol/L) 0.6 ± 1.2 5.2 ± 1.2 0.009
TAC (mmol/L) 23.8 ± 16.3 30.5 ± 16.3 0.78
GSH (μmol/L) 26.3 ± 15.8 25.7 ± 15.8 0.98
MDA (μmol/L) 0.4 ± 0.2 −0.1 ± 0.2 0.02
  1. All values are means± SEs. Values are adjusted for baseline values, age and BMI at baseline
  2. aObtained from ANCOVA
  3. DHEAS dehydroepiandrosterone sulfate, FAI free androgen index, GSH total glutathione, hs-CRP high-sensitivity C-reactive protein, mF-G modified Ferriman Gallwey, MDA malondialdehyde, NO nitric oxide, SHBG sex hormone-binding globulin, TAC total antioxidant capacity