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Table 3 Adjusted changes in metabolic profile of the patients with polycystic ovary syndrome

From: The effects of synbiotic supplementation on hormonal status, biomarkers of inflammation and oxidative stress in subjects with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial

 

Placebo group (n = 30)

Synbiotic group (n = 30)

pa

Total testosterone (ng/mL)

− 0.2 ± 0.1

− 0.3 ± 0.1

0.26

SHBG (nmol/L)

0.7 ± 6.1

19.5 ± 6.1

0.03

FAI

−0.04 ± 0.02

−0.10 ± 0.02

0.04

mF-G scores

−0.1 ± 0.3

−1.3 ± 0.3

0.007

DHEAS (μg/mL)

−0.1 ± 0.1

−0.3 ± 0.1

0.18

hs-CRP (ng/mL)

375.6 ± 339.8

−990.2 ± 339.8

0.006

NO (μmol/L)

0.6 ± 1.2

5.2 ± 1.2

0.009

TAC (mmol/L)

23.8 ± 16.3

30.5 ± 16.3

0.78

GSH (μmol/L)

26.3 ± 15.8

25.7 ± 15.8

0.98

MDA (μmol/L)

0.4 ± 0.2

−0.1 ± 0.2

0.02

  1. All values are means± SEs. Values are adjusted for baseline values, age and BMI at baseline
  2. aObtained from ANCOVA
  3. DHEAS dehydroepiandrosterone sulfate, FAI free androgen index, GSH total glutathione, hs-CRP high-sensitivity C-reactive protein, mF-G modified Ferriman Gallwey, MDA malondialdehyde, NO nitric oxide, SHBG sex hormone-binding globulin, TAC total antioxidant capacity