Table 3 Allele frequency and genotype distribution Val109Asp polymorphic marker of ITLN1 gene in different populations
Populations | HWE, P value | Allele | Allele frequency | Genotype | Genotype frequency (%) | Author(s) |
|---|---|---|---|---|---|---|
Kyrgyz (n = 170) | p = 0.09 | Asp | 0.74 | Asp/Asp | 90 (53.0) | This study |
Val | 0.26 | Val/Asp | 73 (43.0) | |||
Val/Val | 7 (4.0) | |||||
Czech (n = 495) | p = 0.72 | Asp | 0.70 | Asp/Asp | 240 (48.0) | Splichal et al., 2015 [18] |
Val | 0.30 | Val/Asp | 207 (42.4) | |||
Val/Val | 48 (9.6) | |||||
Turkey (n = 42) | p = 0.04 | Asp | 0.76 | Asp/Asp | 22 (52.3) | Yaykasli et al., 2013 [22] |
Val | 0.24 | Val/Asp | 20 (47.6) | |||
Val/Val | 0 | |||||
Turkey (n = 39) | p = 0.28 | Asp | 0.88 | Asp/Asp | 25 (64.0) | Turan, et al., 2013 [14] |
Val | 0.22 | Val/Asp | 11 (28.0) | |||
Val/Val | 3 (8.0) | |||||
Germany (n = 276) | p = 0.036 | Asp | 0.72 | Asp/Asp | 138 (50.0) | Schäffler et al., 2007 [12] |
Val | 0.28 | Val/Asp | 124 (44.9) | |||
Val/Val | 14 (5.1) | |||||
Iran (n = 150) | p = 0.60 | Asp | 0.82 | Asp/Asp | 101 (67.3) | Kohan, 2014 [13] |
Val | 0.18 | Val/Asp | 43 (28.7) | |||
Val/Val | 6 (4.0) |