FSH may be a useful tool to allow early diagnosis of Turner syndrome

BMC Endocrine Disorders

Table 1 Description of the sample: age, karyotype, puberty and results of gonadotropins measurements

Patient	Age at diagnosis	Age at last hormone evaluation^a	Karyotype	Pubertal status	Abnormal measurements/total number of measurements
Patient	Age at diagnosis	Age at last hormone evaluation^a	Karyotype	Pubertal status	FSH	LH
1	NB/MP	LC/A	45,X	Pre-pubertal	9/10	2/10
2	NB/MP	LC/A	45,X	Induced puberty	11/11	3/12
3	NB/MP	LC/A	45,X/46,X,+mar (SRY -)	Induced puberty	16/17	10/17
4	NB/MP	LC/A	45,X	Induced puberty	10/11	6/9
5	NB/MP	LC/A	45,X	Pre-pubertal	12/12	3/12
6	NB/MP	LC/A	45,X	Spontaneous puberty^b	5/14	0/14
7	NB/MP	LC/A	45,X	Induced puberty	10/10	8/10
8	EC	LC/A	45,X/46,XX	Spontaneous puberty^b	0/21	4/21
9	EC	MC	45,X	Pre-pubertal	3/3	2/3
10	EC	LC/A	45,X	Induced puberty	10/11	4/10
11	EC	LC/A	45,X	Pre-pubertal	6/6	1/6
12	EC	LC/A	45,X/46,XX	Spontaneous puberty	2/10	0/8
13	EC	MC	45,X	Pre-pubertal	2/2	1/2
14	EC	LC/A	45,X	Induced puberty	9/9	5/10
15	EC	MC	45,X/46,X,i(Xq)	Pre-pubertal	4/4	0/4

EC early childhood, LC/A late childhood/adolescence, MC midchildhood, mo month, NB/MP newborn/minipuberty, yr. year
^a That of the last visit – in prepubertal patients and those with spontaneous puberty – or the last measurement prior to initiation of hormone replacement therapy
^b Menarche already occurred

ISSN: 1472-6823