Associations between ERα/β gene polymorphisms and osteoporosis susceptibility and bone mineral density in postmenopausal women: a systematic review and meta-analysis

Zhu, Heping; Jiang, Jiannong; Wang, Qiang; Zong, Jun; Zhang, Liang; Ma, Tieliang; Xu, Youjia; Zhang, Leiyan

doi:10.1186/s12902-018-0230-x

Table 2 Characteristics of included studies of lumbar spine BMD, femoral neck BMD, lumbar spine Z value and femoral neck Z value in ERα XbaI genotypes

From: Associations between ERα/β gene polymorphisms and osteoporosis susceptibility and bone mineral density in postmenopausal women: a systematic review and meta-analysis

ERα XbaI			Lumbar Spine BMD (g/cm²)						ERα XbaI			Femoral Neck BMD (g/cm²)
ERα XbaI			XX		Xx		xx		ERα XbaI			XX		Xx		xx
Author	Year	Ethnicity	N	Mean ± SD	N	Mean ± SD	N	Mean ± SD	Author	Year	Ethnicity	N	Mean ± SD	N	Mean ± SD	N	Mean ± SD
Ivanova et al.	2007	Caucasian	73	0.75 ± 0.17	110	0.81 ± 0.06	37	0.87 ± 0.07	Ivanova et al.	2007	Caucasian	73	0.69 ± 0.08	110	0.69 ± 0.04	37	0.65 ± 0.03
Albagha et al.	2001	Caucasian	27	0.88 ± 0.03	89	0.88 ± 0.02	90	0.85 ± 0.02	Albagha et al.	2001	Caucasian	27	0.77 ± 0.03	89	0.73 ± 0.01	90	0.72 ± 0.02
Aerssens et al.	2000	Caucasian	14	0.94 ± 0.21	64	0.93 ± 0.22	57	0.88 ± 0.16	Aerssens et al.	2000	Caucasian	14	0.73 ± 0.03	64	0.68 ± 0.09	57	0.70 ± 0.20
Jeedigunta et al.	2010	Asian	60	0.89 ± 0.15	133	0.86 ± 0.13	54	0.64 ± 0.16	Kurt et al.	2012	Caucasian	41	0.79 ± 0.09	94	0.8 ± 0.08	40	0.83 ± 0.10
Kurt et al.	2012	Caucasian	41	0.95 ± 0.12	94	0.92 ± 0.12	40	0.93 ± 0.10	Ge et al.	2006	Asian	37	0.70 ± 0.10	134	0.68 ± 0.07	26	0.67 ± 0.07
Kurabayashi et al.	1999	Asian	1	1.18 ± 0.00	20	0.92 ± 0.04	61	0.92 ± 0.02	Pérez et al.	2008	Caucasian	7	0.59 ± 0.02	36	0.58 ± 0.01	20	0.56 ± 0.02
Ge et al.	2006	Asian	37	0.73 ± 0.08	134	0.74 ± 0.09	26	0.75 ± 0.13
Pérez et al.	2008	Caucasian	7	0.70 ± 0.02	31	0.67 ± 0.02	24	0.66 ± 0.02
ERα XbaI			Lumbar Spine Z value						ERα XbaI			Femoral Neck Z value
ERα XbaI			XX		Xx		xx		ERα XbaI			XX		Xx		xx
Author	Year	Ethnicity	N	Mean ± SD	N	Mean ± SD	N	Mean ± SD	Author	Year	Ethnicity	N	Mean ± SD	N	Mean ± SD	N	Mean ± SD
Shang et al.	2016	Asian	146	−1.98 ± 0.91	146	−1.65 ± 0.02	6	−0.35 ± 2.19	Ivanova et al.	2007	Caucasian	73	−2.00 ± 0.00	110	−2.00 ± 0.00	37	−1.90 ± 0.00
Ivanova et al.	2007	Caucasian	73	−2.10 ± 0.00	110	−0.6 ± 0.00	37	−0.1 ± 0.00	Albagha et al.	2001	Caucasian	27	−2.00 ± 0.23	89	−0.42 ± 0.10	90	−0.52 ± 0.12
Albagha et al.	2001	Caucasian	27	−0.34 ± 0.20	89	−0.29 ± 0.11	90	−0.47 ± 0.11	An et al.	2000	Asian	10	0.42 ± 0.57	84	0.11 ± 0.66	152	−0.32 ± 0.76
An et al.	2000	Asian	10	0.48 ± 0.49	84	0.12 ± 0.85	152	−0.26 ± 0.58

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