Table 1 Characteristics of groups before treatment
Variables | Metformin-insulin n = 29 | İnsulin-only n = 29 | p value |
|---|---|---|---|
Female (%) | 41.4 | 48.3 | 0.597 |
Metabolic syndrome (%) | 44.8 | 41.4 | 0.585 |
Overweight/obesity (%) | 31.0 | 24.1 | 0.291 |
Hypertension (%) | 27.6 | 13.8 | 0.195 |
Hyperlipidemia (%) | 31.0 | 37.9 | 0.581 |
Antihypertensive drugs (%) | 12.3 | 7.2 | 0.127 |
Antilipidemic drugs (%) | 14.1 | 16.7 | 0.895 |
Age (yr) | 30.4 ± 7.5 | 27.5 ± 6.3 | 0.127 |
Duration of diabetes (yr) | 13.1 ± 6.8 | 10.9 ± 6.1 | 0.173 |
Body weight (kg) | 69.23 ± 10.13 | 66.96 ± 11.50 | 0.429 |
BMI (kg/m2) | 24.43 ± 2.87 | 24.02 ± 3.46 | 0.446 |
Waist circumference (cm) | 82.39 ± 8.28 | 80.65 ± 9.59 | 0.368 |
Risk factors of metabolic syndrome (n) | 2.27 ± 1.13 | 2.31 ± 1.03 | 0.904 |
Creatinine (mg/dl) | 0.81 ± 0.19 | 0.79 ± 0.14 | 0.124 |
FPG (mg/dl) | 192.37 ± 56.01 | 174.48 ± 53.60 | 0.232 |
PPG (mg/dl) | 277.31 ± 57.43 | 250.04 ± 64.35 | 0.100 |
HbA1c (%) | 9.55 ± 1.43 | 9.22 ± 1.79 | 0.441 |
Total cholesterol (mg/dl) | 183.43 ± 59.45 | 177.25 ± 26.89 | 0.836 |
Triglycerides (mg/dl) | 141.93 ± 131.33 | 136.96 ± 117.98 | 0.844 |
HDL cholesterol (mg/dl) | 54.96 ± 13.59 | 50.28 ± 11.68 | 0.233 |
LDL cholesterol (mg/dl) | 105.46 ± 39.25 | 107.52 ± 27.26 | 0.566 |
Systolic blood pressure (mmHg) | 122.75 ± 16.74 | 119.48 ± 16.70 | 0.441 |
Diastolic blood pressure (mmHg) | 78.13 ± 12.76 | 76.89 ± 11.83 | 0.690 |
Total daily insulin dose (IU/kg body weight/d) | 0.92 ± 0.27 | 0.98 ± 0.30 | 0.232 |