Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

Heltberg, Andreas; Siersma, Volkert; Andersen, John Sahl; Ellervik, Christina; Brønnum-Hansen, Henrik; Kragstrup, Jakob; de Fine Olivarius, Niels

doi:10.1186/s12902-017-0227-x

Table 2 Any diabetes-related outcome and all-cause mortality during 19 years of follow-up, according to socio-demographic group

From: Socio-demographic determinants and effect of structured personal diabetes care: a 19-year follow-up of the randomized controlled study diabetes Care in General Practice (DCGP)

	No. of patients without outcome at diabetes diagnosis (routine/ structured)	No. (%) of patients with outcome			Absolute risk (events per 1000 patient years)			Hazard ratio (HR)^a for structured- versus routine care (=reference group)
		Routine care	Structured personal care	p value^b	Routine care	Structured personal care	p value^c	Adjusted for age, sex and clustering	p value^d	Additionally adjusted for clinical and behavioral variables^f	p value^d	Interaction p value^e
Education^f Any diabetes-related endpoint												0.11
Basic	377/461	281 (74.5)	313 (67.9)	0.04	89.2	74.5	0.01	0.80 (0.67–0.94)	0.008	0.75 (0.63–0.89)	0.0008
Higher	108/124	72 (66.7)	74 (59.7)	0.27	61.5	53.0	0.31	0.94 (0.69–1.28)	0.69	1.01 (0.73–1.40)	0.97
All-cause mortality												0.35
Basic	459/574	343 (74.7)	410 (71.4)	0.26	66.4	63.0	0.45	0.94 (0.81–1.08)	0.37	0.90 (0.77–1.06)	0.20
Higher	129/149	78 (60.5)	84 (56.4)	0.56	47.8	43.0	0.48	1.03 (0.78–1.37)	0.84	1.06 (0.78–1.43)	0.73
Employment status^g Any diabetes-related endpoint												0.50
Out of labor market	148/165	109 (73.7)	106 (64.2)	0.07	75.2	61.7	0.06	0.76 (0.58–1.01)	0.06	0.73 (0.55–0.97)	0.03
In labor market	148/192	90 (60.8)	108 (56.3)	0.38	51.5	44.4	0.23	0.87 (0.67–1.14)	0.32	0.84 (0.63–1.12)	0.23
All-cause mortality												0.87
Out of labor market	181/203	116 (64.1)	127 (62.6)	0.75	50.8	48.1	0.67	0.94 (0.74–1.20)	0.61	0.90 (0.69–1.18)	0.44
In labor market	157/208	62 (39.5)	78 (37.5)	0.69	25.2	24.1	0.76	1.02 (0.74–1.39)	0.92	0.93 (0.66–1.31)	0.68
Residence Any diabetes-related endpoint												0.033
Rural	137/133	94 (68.6)	89 (66.9)	0.09	67.1	77.7	0.24	1.01 (0.75–1.36)	0.95	1.07 (0.77–1.48)	0.70
Urban	353/455	263 (74.5)	300 (65.9)	0.01	91.0	67.4	<0.0001	0.75 (0.63–0.88)	0.0007	0.71 (0.60–0.85)	0.0001
All-cause mortality												0.21
Rural	161/153	108 (67.1)	112 (73.2)	0.28	54.0	64.9	0.14	1.09 (0.83–1.43)	0.55	1.08 (0.83–1.42)	0.56
Urban	435/575	321 (73.8)	391 (68.0)	0.04	66.8	58.1	0.05	0.91 (0.78–1.06)	0.21	0.89 (0.75–1.05)	0.16
Civil status Any diabetes-related endpoint												0.46
Living alone	158/176	120 (76.0)	127 (72.2)	0.42	101.6	92.7	0.41	0.83 (0.64–1.08)	0.16	0.88 (0.68–1.15)	0.36
Cohabiting	344/426	244 (70.9)	273 (64.1)	0.04	74.4	62.4	0.02	0.83 (0.70–0.98)	0.03	0.78 (0.65–0.93)	0.007
All-cause mortality												0.32
Living alone	198/236	167 (84.3)	195 (82.6)	0.62	87.5	85.1	0.80	0.84 (0.68–1.03)	0.09	0.84 (0.68–1.03)	0.09
Cohabiting	408/507	267 (65.4)	314 (61.9)	0.31	52.6	49.3	0.41	1.00 (0.85–1.19)	0.98	0.97 (0.80–1.17)	0.71

^aThe Hazard Ratio (HR), from a Cox proportional hazard regression model, reference group was routine care group. The corresponding 95% CIs and p values are determined using a sandwich estimator for the variance to account for clustering of patients within practices; ^b p value from a Rao-Scott χ² test: a Pearson χ² test adjusted for clustering of patients with general practitioners; ^c p. value from a log-rank test; ^dTests whether the effect of randomization differs between groups; ^e Adjusted for age at diagnosis, sex, clustering, BMI, hypertension, HbA_1c, total cholesterol, urinary albumin, physical activity, smoking, known cardiovascular disease (see Table 1) and use of glucose- or lipid-lowering medication and antihypertensive therapy; ^f highest attained education level (Basic school education only/ higher level of education), ^g We excluded retired for this analysis

Back to article page

ISSN: 1472-6823

Contact us

General enquiries: journalsubmissions@springernature.com

BMC Endocrine Disorders

Contact us