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Table 3 Adjusted potential variables for the prediction of the HbA1c responses according to the stratified classification

From: Effectiveness and safety of exenatide in Korean patients with type 2 diabetes inadequately controlled with oral hypoglycemic agents: an observational study in a real clinical practice

 

HbA1c reduction ≥0.6%

HbA1c <7.5%

HbA1c reduction ≥9.8% from baseline

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Male sex

1.47 (0.94–2.29)

0.09

Not determined

 

1.40 (0.90–2.15)

0.13

HbA1c ≥8.5%

3.13 (1.95–5.04)

<0.001

0.13 (0.08–0.22)

<0.001

2.36 (1.48–3.77)

<0.001

FPG ≥160 mg/dL

1.60 (1.01–2.54)

0.047

0.58 (0.35–0.97)

0.037

1.47 (0.93–2.34)

0.10

Duration of diabetes ≥5 years

0.997 (0.995–1.000)

0.053

0.994 (0.991–0.997)

<0.001

0.997 (0.994–1.000)

0.043

Number of previous antidiabetic medication (2 vs. 0 or 1)

1.07 (0.67–1.71)

0.79

0.91 (0.52–1.58)

0.74

1.28 (0.80–2.05)

0.31

  1. Abbreviations: OR odd ratio, HbA1c Hemoglobin A1c, FPG Fasting plasma glucose
  2. Multivariate logistic regression test; References of dependent variables in each stratum, Group 2, Group B, and group II, respectively