From: Thyroid function and metabolic syndrome in the population-based LifeLines cohort study
 | Men | Women | P-value |
---|---|---|---|
 | N = 11.819 | N = 14.900 |  |
Age (years) | 46 ± 13 | 45 ± 13 | <0.001 |
BMI (kg/m2) | 26.5 ± 3.5 | 25.7 ± 4.4 | <0.001 |
Waist (cm) | 96 ± 10 | 87 ± 12 | <0.001 |
Waist-hip ratio | 0.97 ± 0.07 | 0.87 ± 0.07 | <0.001 |
FT3 | 5.46 ± 0.53 | 5.10 ± 0.52 | <0.001 |
FT4 | 16.1 ± 1.9 | 15.5 ± 1.8 | <0.001 |
TSH | 2.11 ± 0.85 | 2.20 ± 0.90 | <0.001 |
Normal weight/overweight | |||
/obesity (n,%) | 35.1/51.0/13.9 | 37.2/47.9/14.9 | NS |
Current/never smokers (%) | 17.5/42.3 | 33.1/43.4 | <0.001/NS |
Systolic BP (mmHg) | 131 ± 14 | 122 ± 15 | <0.001 |
Diastolic BP (mmHg) | 77 ± 9 | 72 ± 9 | <0.001 |
Heart rate (b/min) | 70 ± 11 | 72 ± 10 | <0.001 |
Creatinine (mcmol/l) | 83 ± 12 | 68 ± 9 | <0.001 |
Fasting glucose (mmol/l) | 5.2 ± 0.8 | 4.9 ± 0.7 | <0.001 |
HbA1c (%) | 5.6 ± 0.4 | 5.6 ± 0.4 | <0.001 |
Total cholesterol (mmol/l) | 5.16 ± 1.00 | 5.01 ± 0.98 | <0.001 |
HDL-cholesterol (mmol/l) | 1.29 ± 0.31 | 1.60 ± 0.39 | <0.001 |
LDL-cholesterol (mmol/l) | 3.38 ± 0.89 | 3.06 ± 0.88 | <0.001 |
Triglycerides (mmol/l) | 1.15 (0.84–1.66) | 0.86 (0.65–1.18) | <0.001 |
% with metabolic syndrome | 20.7 | 11.8 | <0.001 |
% with type 2 diabetes | 2.9 | 1.7 | <0.001 |