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Table 4 Treatment during care at center by presenting status and final biochemical control status

From: Long-term treatment outcomes of acromegaly patients presenting biochemically-uncontrolled at a tertiary pituitary center

Final Biochemical Control

Presenting Uncontrolled Without Prior Treatment for Acromegaly

n = 40 (54.1%)

Presenting Uncontrolled With Prior Treatment for Acromegaly

n = 34 (45.9%)

All

N = 74

Controlled

n = 33 (82.5%)

Uncontrolled

n = 7 (17.5%)

Controlled

n = 17 (50.0%)

Uncontrolled

n = 17 (50.0%)

Treatment Patterns

 Surgery and medication

17

4

2

4

27

(51.5)

(57.1)

(11.8)

(23.5)

(36.5)

 Medication only

2

2

10

12

26

(6.1)

(28.6)

(58.8)

(70.6)

(35.1)

 Surgery only

14

1

3

1

19

(42.4)

(14.3)

(17.6)

(5.9)

(25.7)

 No treatment

0

0

2

0

2

(0.0)

(0.0)

(11.8)

(0)

(2.7)

Pituitary surgery

31

5

5

5

46

(93.9)

(71.4)

(29.4)

(29.4)

(62.2)

Pharmacologic treatment

19

6

12

16

53

(57.6)

(85.7)

(70.6)

(94.1)

(71.6)

 Somatostatin analogues

15

4

9

15

43

(45.5)

(57.1)

(52.9)

(88.2)

(58.1)

 Pasireotide

0

0

1

0

1

(0.0)

(0.0)

(5.9)

(0.0)

(1.4)

 Dopamine agonists

8

2

6

10

26

(24.2)

(28.6)

(35.3)

(58.8)

(35.1)

 Pegvisomant

5

1

2

4

12

(15.2)

(14.3)

(11.8)

(23.5)

(16.2)

  1. Somatostatin analogues include octreotide LAR, octreotide SA, and lanreotide; dopamine agonists include bromocriptine and cabergoline; dopamine agonists include bromocriptine and cabergoline