Table 1 Baseline patient characteristics by presenting status
|  | Presenting Uncontrolled Without Prior Treatment for Acromegaly n = 40 (54.1%) | Presenting Uncontrolled with Prior Treatment for Acromegaly n = 34 (45.9%) | All N = 74 |
|---|---|---|---|
Age at index date, yeara | |||
 mean | 44.7 | 50.1 | 47.2 |
 (SD) | (15.5) | (15.6) | (15.6) |
Age at diagnosis, yearb | |||
 n | 35 | 31 | 66 |
 mean | 43.8 | 42.5 | 43.2 |
 (SD) | (15.5) | (14.0) | (14.7) |
Female | |||
 n | 16 | 16 | 32 |
 (%) | (40.0) | (47.1) | (43.2) |
Race/ethnicity | |||
 Caucasian | |||
  n | 30 | 25 | 55 |
  (%) | (75.0) | (73.5) | (74.3) |
 Asian | |||
  n | 5 | 5 | 10 |
  (%) | (12.5) | (14.7) | (13.5) |
 Hispanic | |||
  n | 4 | 4 | 8 |
  (%) | (10.0) | (11.8) | (10.8) |
 Other | |||
  n | 1 | 0 | 1 |
  (%) | (2.5) | (0.0) | (1.4) |
Years of follow-up at center | |||
 mean | 5.1 | 8.5 | 6.7 |
 (SD) | (4.4) | (5.7) | (5.3) |
 min - max | 0.3–23.0 | 0.2–21.3 | 0.2–23.0 |
 median | 4.2 | 7.8 | 4.9 |
Tumor Sizec | |||
  n | 36 | 29 | 65 |
 Macroadenoma | |||
  n | 33 | 26 | 59 |
  (%) | (91.7) | (89.7) | (90.8) |
 Microadenoma | |||
  n | 3 | 3 | 6 |
  (%) | (8.3) | (10.3) | (9.2) |
Abnormal finding on MRI or CT | |||
 n | 25 | 15 | 40 |
 (%) | (62.5) | (44.1) | (54.1) |
Hormonal Abnormalities | |||
 Prolactin elevation | |||
  n | 0 | 1 | 1 |
  (%) | (0.0) | (2.9) | (1.4) |
 Adrenal insufficiency | |||
  n | 4 | 3 | 7 |
  (%) | (10.0) | (8.8) | (9.5) |
 Gonadal insufficiency | |||
  n | 5 | 4 | 9 |
  (%) | (12.5) | (11.8) | (12.2) |
 Hypothyroidism | |||
  n | 4 | 6 | 10 |
  (%) | (10.0) | (17.6) | (13.5) |