Table 2 Comparison of the pro-inflammatory cytokine profile before and after 12 weeks treatment with metformin or rimonabant
Parameter | Metformin group (n = 10) | Rimonabant group (n = 10) | ||||
|---|---|---|---|---|---|---|
Baseline | 12 weeks | P-value | Baseline | 12 weeks | P-value | |
IL-1β | 86 ± 56 | 105 ± 89 | 0.17 | 85 ± 77 | 91 ± 91 | 0.32 |
IL-6 | 12 ± 6 | 13 ± 7 | 0.31 | 17 ± 8 | 18 ± 9 | 0.31 |
IL-7 | 249 ± 18 | 252 ± 31 | 0.69 | 235 ± 47 | 263 ± 49 | 0.11 |
IL-10 | 23 ± 32 | 27 ± 30 | 0.29 | 10 ± 6 | 10 ± 6 | 0.92 |
IL-12 | 203 ± 60 | 223 ± 83 | 0.11 | 201 ± 41 | 207 ± 33 | 0.50 |
TNF-α | 7 ± 3 | 8 ± 4 | 0.33 | 9 ± 4 | 9 ± 4 | 0.99 |
MCP-1 | 294 ± 66 | 298 ± 88 | 0.80 | 279 ± 60 | 307 ± 58 | 0.6 |
INF-γ | 30 ± 10 | 30 ± 9 | 0.83 | 30 ± 7 | 36 ± 9 | 0.6 |