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Table 3 Association between type 2 diabetic status and inflammatory markers

From: Elevated C-reactive protein, interleukin 6, tumor necrosis factor alpha and glycemic load associated with type 2 diabetes mellitus in rural Thais: a cross-sectional study

 

Normal vs. pre-diabetic group

Normal vs. T2DM group

Crude OR (95% CI)

P

Adjusted ORa (95% CI)

P

Crude OR (95% CI)

P

Adjusted ORa (95% CI)

P

CRP (mg/dl)

 < 1.00

1

 

1

 

1

 

1

 

 ≥ 1.00

2.02 (1.09,3.75)

0.026

1.89 (0.98,3.64)

0.059

8.10 (2.74, 23.97)

0.000

7.51 (2.11,26.74)

0.002

TNF-α (pg/ml)

 < 30.23

1

 

1

 

1

 

1

 

 30.23–72.53

0.40 (0.18, 0.85)

0.018

0.37 (0.17,0.81)

0.013

0.61 (0.21,1.74)

0.357

0.67 (0.18,2.46)

0.548

 > 72.53

0.77 (0.33,1.77)

0.533

0.78 (0.33, 1.84)

0.563

1.25 (0.42,3.70)

0.691

1.56 (0.39,6.14)

0.528

IL6 (pg/ml)

 < 6.14

1

 

1

 

1

 

1

 

 6.14–61.91

1.54 (0.75,3.18)

0.242

1.66 (0.77,3.54)

0.192

1.68 (0.56,5.01)

0.351

3.22 (0.82,12.68)

0.094

 > 61.91

1.64 (0.76,3.53)

0.206

1.88 (0.85,4.18)

0.122

3.76 (1.33,10.68)

0.013

4.95 (1.28,19.11)

0.020

  1. Abbreviations: CRP C-reactive protein, TNF-α tumor necrosis factor alpha, IL6 interleukin 6, T2DM type 2 diabetes mellitus
  2. aOR was adjusted for age, gender, and body mass index
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