Table 1 Baseline parameters of non-obese and obese patients with PCOS and normal controls (mean ± SD), showing the elevated androgen levels found in PCOS subjects, the elevated ADTG: DHEAS ratio and increased insulin resistance found for the obese PCOS patients
Parameters | Nonobese (n=11) | Obese (n=14) | Controls (n=11) | p value between nonobese and obese PCOS | p value between obese PCOS and controls | p value between nonobese PCOS and controls |
|---|---|---|---|---|---|---|
Age (years) | 23.3 ± 4.5 | 26.0 ± 4.1 | 32.6 ± 4.9 | 0.13 | <0.01 | 0.01 |
BMI (kg/m2) | 22.9 ± 1.4 | 36.8 ± 4.8 | 26.0 ± 4.7 | <0.01 | <0.01 | 0.051 |
Total Testosterone (nmol/L) | 1.7 ± 0.7 | 1.6 ± 0.7 | 1.0 ± 0.4 | 0.73 | <0.02 | <0.02 |
SHBG (nmol/L) | 42.5 ± 16.3 | 25.4 ± 10.6 | 61.4 ± 21.8 | <0.01 | <0.01 | <0.03 |
FAI | 4.3 ± 1.7 | 7.3 ± 4.4 | 1.9 ± 1.0 | <0.03 | <0.01 | <0.01 |
DHEAS (μmol/L) | 7.6 ± 2.3 | 5.5 ± 1.7 | 3.3 ±1.4 | <0.05 | <0.01 | <0.01 |
ADTG (nmol/L) | 213.7 ± 82.3 | 216.9 ± 121.7 | 97.7 ± 52.0 | 0.9 | <0.01 | <0.01 |
ADTG/DHEAS ratio (nmol/umol) | 28 ± 5 | 39 ± 6 | 29 ± 4 | <0.01 | <0.01 | 0.85 |
Androstenedione (nmol/L) | 7.3 ± 2.8 | 6.9 ± 3.6 | 3.2 ± 1.5 | 0.73 | <0.01 | <0.01 |
HOMA-IR | 1.6 ± 0.7 | 4.4 ± 2.8 | 1.6 ± 0.7 | <0.01 | <0.01 | 1.00 |