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Table 2 Adjusted ORs (95% CI) of non-alcohol fatty liver disease according to quartiles of calf circumference

From: Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study

Quartiles of calf circumference
  Q1: ≤32.9 cm Q2: 33-35 cm Q3: 35.1-36.9 cm Q4: ≥37 cm  
Model 1 1 (reference) 1.84 (1.64-2.06) 3.01 (2.68-3.38) 5.59 (4.94-6.34) <0.0001
Model 2 1 (reference) 1.70 (1.50-1.93) 2.84 (2.50-3.23) 5.07 (4.43-5.81) <0.0001
Model 3 1 (reference) 1.30 (1.14-1.48) 1.83 (1.59-2.10) 2.85 (2.46-3.30) <0.0001
Model 4 1 (reference) 1.29 (1.12-1.48) 1.85 (1.60-2.14) 2.73 (2.34-3.19) <0.0001
  1. Model 1: adjusted for age, sex (not for sex-stratified analysis). Model 2: further adjusted for physical activity (low, moderate, or high), smoking (yes/no), family history of diabetes (yes/no), self-reported CHD (yes/no), stroke (yes/no), and hypertension (yes/no) was included in the model. Model 3: further adjusted for waist circumference and inflammatory factors (CRP and IL-6, continuous variables). Model 4: further adjusted for BMI and lipid profiles (total cholesterol, triglycerides, HDL- cholesterol and LDL- cholesterol)