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Table 2 Comparison of absolute change in clinical parameters of PCOS patients among different treatment groups

From: Short-term effectiveness of low dose liraglutide in combination with metformin versus high dose liraglutide alone in treatment of obese PCOS: randomized trial

 

LIRA3

LIRA1.2 + MET2000

P a

Characteristic

Absolute change mean ± SD

Absolute change mean ± SD

 

Weight (kg)

−6.3 ± 3.7

−3.6 ± 2.5

0.062

BMI (kg/m2)

−2.2 ± 1.3

−1.3 ± 0.9

0.050

Waist circumference (cm)

−4.2 ± 3.4

−2.2 ± 6.2

0.014

Androstenedione (nmol/l)

0.6 ± 2.7

−2.0 ± 6.0

0.376

Total testosterone (nmol/l)

−0.2 ± 0.3

−0.3 ± 0.6

0.285

Free testosterone (pmol/l)

0.6 ± 3.3

−0.7 ± 5.3

0.482

SHBG (nmol/l)

7.3 ± 14.2

19.5 ± 71.4

0.376

Glu 0 min OGTT (mmol/l)

−0.1 ± 0.4

−0.4 ± 0.6

0.734

Glu 120 min OGTT (mmol/l)

−1.2 ± 0.8

−1.1 ± 1.4

0.804

Insulin 0 min OGTT (mU/l)

−2.5 ± 9.3

−7.7 ± 16.3

0.571

Insulin 120 min OGTT (mU/l)

−30.9 ± 29.5 [2]

−9.7 ± 73.4

0.560

HOMA IR

−0.7 ± 2.3

−2.1 ± 3.9

0.427

Cholesterol (mmol/l)

0.0 ± 0.4

−0.3 ± 0.6 [1]

0.094

HDL cholesterol (mmol/l)

0.0 ± 0.1

0.0 ± 0.1 [1]

0.793

LDL cholesterol (mmol/l)

0.0. ± 0.3

−0.3 ± 0.4 [1]

0.038

TG (mmol/l)

0.1 ± 0.4

−0.2 ± 0.4 [1]

0.128

  1. acompared with nonparametric Mann–Whitney test, bold values indicate statistically significant differences