Table 2 Anthropometric and metabolic characteristics of patients during the study
Parameter | T0 | T1 | T2 | Friedman Test | P(T0-T1) | P(T1-T2) | P(T0-T2) |
|---|---|---|---|---|---|---|---|
Age (years) | 42.3 ± 2.2 | ||||||
Gender (female/male) | 18/11 | ||||||
BMI (kg/m2) | 46.4 ± 1.7 | 38.3 ± 1.4 | 36.3 ± 1.4 | *** | *** | * | *** |
MAP (mmHg) | 109.0 ± 2.6 | 93.4 ± 2.3 | 103.5 ± 2.4 | *** | *** | * | n.s. |
Fasting glucose (mg/dl) | 110.2 ± 7.0 | 90.7 ± 2.1 | 89.7 ± 2.2 | *** | *** | n.s. | *** |
2 h-Glucose OGTT (mg/dl) | 117.9 ± 6.6 | 117.5 ± 4.7 | 93.2 ± 3.6 | *** | n.s. | *** | *** |
HOMA-IR | 7.8 ± 1.2 | 3.3 ± 0.3 | 3.8 ± 0.5 | *** | *** | n.s. | ** |
T-cholesterol (mg/dl) | 192.2 ± 7.6 | 157.4 ± 5.5 | 181.0 ± 6.8 | *** | *** | *** | n.s. |
LDL (mg/dl) | 110.3 ± 6.4 | 98.3 ± 4.5 | 105.8 ± 5.3 | * | ** | n.s. | n.s. |
HDL (mg/dl) | 53.4 ± 4.4 | 38.9 ± 1.9 | 53.8 ± 2.6 | *** | *** | *** | n.s. |
Triglycerides (mg/dl) | 149.5 ± 22.9 | 100.8 ± 5.2 | 123.9 ± 30.9 | ** | *** | n.s. | ** |
Adiponectin (μg/ml) | 4.8 ± 0.4 | 6.7 ± 0.5 | 7.9 ± 0.7 | *** | *** | * | *** |
Leptin (μg/l) | 54.1 ± 5.9 | 20.5 ± 2.7 | 32.9 ± 5.8 | *** | *** | ** | *** |
LAR | 12.7 ± 1.4 | 3.5 ± 0.5 | 5.7 ± 1.1 | *** | *** | * | *** |
hsCRP (mg/l) | 10.1 ± 2.1 | 6.1 ± 1.1 | 3.4 ± 0.8 | *** | * | ** | *** |