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Table 2 Characteristics of the boys with early puberty at presentation

From: Familial early puberty: presentation and inheritance pattern in 139 families

 

PP (n = 25)

AP (n = 13)

Total (n = 38)

n

m ± SD

n

m ± SD

n

m ± SD

Age at onset, years

25

8.8 ± 0.6

12

10.7 ± 0.5

37

9.5 ± 1.1

Age at evaluation, years

25

9.8 ± 1

13

11.4 ± 1.3

38

10.3 ± 1.3

Height, SDS

25

2.2 ± 1.6

12

0.1 ± 1.3

37

1.6 ± 1.8

BMI, SDS

24

1.2 ± 1

12

0.2 ± 1

36

0.9 ± 1.1

BA advance, years

24

1.4 ± 1.2

10

0.3 ± 1.1

34

1.1 ± 1.3

Tanner pubic hair

24

3 ± 1

11

2.8 ± 1.2

35

3 ± 1

Testicular volume, mm

21

36.4 ± 9.3

10

39.8 ± 7

31

38 ± 8.6

Age at M mothers, years

23

11.3 ± 1.5

13

11.4 ± 1.5

36

11.4 ± 1.5

LH peak, IU/L

22

14.7 ± 10.5

10

15.9 ± 5.2

32

15.1 ± 9.1

FSH peak, IU/L

22

5.4 ± 5.3

10

4.8 ± 5.6

32

5.2 ± 5.3

LH/FSH peak ratio

22

3.4 ± 2.7

10

6.1 ± 4.4

32

4.2 ± 3.5

Testosterone, ng/mL

25

1.8 ± 2.7

12

1.1 ± 1.1

37

1.6 ± 2.3

GnRH analog treatment

25

2

13

2

38

4 (10 %)

  1. PP Central precocious puberty, AP Advanced puberty, M menstruation