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Table 4 Studies in Chronic Fatigue Syndrome (N = 13): Methods of assessment and respective results

From: Adrenal fatigue does not exist: a systematic review

Procedure Number of studies (% of total) Not different (%) Decreased (%) Increased (%)
MSC 8 (61.5 %) 5 (62.5 %) 2 (25.0 %) 1 (12.5 %)
SCR 6 (46.2 %) 5 (83.3 %) 1 (16.7 %) -
AUC 6 (46.2 %) 3 (50.0 %) 2 (33.3 %) 1 (16.7 %)
NSC 5 (38.5 %) 4 (80.0 %) 1 (20.0 %)  
DAC 3 (23.1 %) 3 (100.0 %) - -
CAR 3 (23.1 %) 2 (66.7 %) 1 (33.3 %) -
ACTH 2 (15.4 %) 2 (100.0 %) - -
DST 2 (15.4 %) 1 (50.0 %) 1 (50.0 %) -
UFC 2 (15.4 %) 1 (50.0 %) 1 (50.0 %) -
CST 1 (7.7 %) - 1 (100.0 %) -
  1. Legends: (*): MSC morning serum (& salivary) cortisol, SCR salivary cortisol rhythm, AUC area under-the-curve (estimated cortisol release), NSC night salivary cortisol, DAC direct awakening cortisol, CAR cortisol awakening response, ACTH adrenocorticotropic hormone, DST dexamethasone suppression test, UFC 24 h-urinary free cortisol, CST cosyntropin stimulation test