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Table 1 Demographic and laboratory variables in T1DM patients and controls

From: Retinal blood flow is increased in type 1 diabetes mellitus patients with advanced stages of retinopathy

 

Controls

T1DM no DRP

T1DM non-proliferative DRP

T1DM proliferative DRP (treated)

P

N

44

32

11

33

 

Age (years)

38 (11.3)

38 (8.7)

36 (5.4)

45 (7.7)

<0.001

Gender (m/f)

18/26

10/22

4/7

15/18

0.687

Systolic blood pressure (mmHg)

124 (12)

131 (17)

121 (11)

136 (19)

<0.01

Diastolic blood pressure (mmHg)

78 (8)

77 (9)

76 (5)

77 (9)

0.941

Diabetes duration (years)

22 (8.5)

22 (7.6)

34 (6.6)

<0.001

Hypertension (%)a

8 (25 %)

2 (18 %)

21 (66 %)

<0.001

Current blood glucose (mmol/l)b

8.2 (3.2)

8.4 (3.2)

9.7 (5.0)

0. 321

HbA1c (%)

5.3 (0.2)

7.9 (0.9)

7.8 (1.1)

8.1 (1.4)

<0.001

Albumin-to-creatinine ratioc

0.8 (1.0)

0.5 (0.6)

3.3 (6.7)

0.059

Neuropathy (%)d

1 (3)

0

15 (47)

<0.01

Nephropathy (%)e

0

0

6 (19)

<0.01

  1. Data are mean ± standard deviation or absolute number with percentages. P-values for overall one-way ANOVA are shown
  2. aHypertension was defined as a systolic blood pressure of 140 mmHg or above, a diastolic blood pressure of 90 mmHg or above or use of anti-hypertensive medication
  3. bCurrent blood glucose level was measured using a finger prick
  4. cAlbumin-to-creatinine ratio was determined in 24-h urine sampling
  5. dNeuropathy was self-reported or obtained from medical records
  6. eNephropathy was based on a 24-h urine sample and defined as an ACR of 2.5 or above for men and 3.5 for women