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Table 2 Urine steroid profile in 43 patients with adrenocortical cancer

From: Adrenocortical cancer: mortality, hormone secretion, proliferation and urine steroids – experience from a single centre spanning three decades

 

Normal

↑↑

Not reported

Androgens

10

9

19

5

3 β-hydroxy-5-enestereoids

8

6

18

9

Pregnantriol

16

7

12

8

Tetrahydro-11-deoxycortisol

16

7

12

8

Cortisol metabolites

15

10

13

5

  1. Normal, within reference
  2. ↑ Intermediate levels ≤ three times references
  3. ↑↑ Pathologic levels > three times references
  4. Androgens: Androsterone normal < 13 umol/24 h and/or etiocholanolone < 14.8 umol/24 h
  5. 3β-hydroxy-5-ene steroids: dehydroepiandrosterone [DHA] normal < 3.8 umol/24 h, pregnenolone < 7.4 umol/24 h or 17α-hydroxypregnenolone < 7.4 umol/24 h
  6. Pregnanetriol < 6 umol/24 h
  7. Tetrahydro-11-deoxycortisol (THS) < 0 umol/24 h
  8. Cortisolmetabolites < 35 umol/24 h, these include: Tetrahydrocortison, tetrahydrocortisol, allo- tetrahydrocortisol, α-cortolon, β-cortolon, β-cortol, α-cortol