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Table 3 Estimated hazard ratios from a Cox proportional hazard regression with time to hospital readmission as the dependent variable. After propensity-score adjustment, and controlling for demographic and other patient characteristics, patients on a sulfonylurea were 29 % more likely to be readmitted to the hospital than patients on another oral antihyperglycemic agent. Unmarried patients and patients with eye disease were also more likely to be readmitted

From: Sulfonylurea use and the risk of hospital readmission in patients with type 2 diabetes

Independent variable a

Hazard ratio

95 % confidence interval

p-value

Sulfonylurea

1.29

1.01–1.65

0.042

Age

1.01

0.98–1.03

0.749

Male

0.96

0.61–1.28

0.838

Race

   

 African American

0.89

0.66–1.28

0.512

 Other

0.96

0.61–1.52

0.867

 White

1.00

  

Region

   

 Northeast

1.00

0.65–1.44

0.864

 Midwest

0.86

0.62–1.18

0.349

 West

1.28

0.94–1.74

0.110

 South

1.00

  

Unmarried

1.44

1.04–1.99

0.030

Period of first hospital admission

   

 1999–2003

0.69

0.37–1.28

0.235

 2008–2010

0.49

0.31–0.78

0.003

 2004–2007

1.00

  

Cardiovascular disease

1.30

0.89–1.89

0.147

Renal disease

1.34

0.90–1.98

0.589

Eye disease

1.45

1.06–2.00

0.022

Perceived health status

   

 Good

0.76

0.49–1.18

0.221

 Fair or poor

1.09

0.70–1.67

0.709

 Excellent or very good

1.00

  

Physical limitations

1.09

0.79–1.51

0.589

  1. a The patient propensity score was also included in the regression. Its estimated coefficient was not statistically significant (p > 0.100)