Fig. 3From: Successful every-other-day liothyronine therapy for severe resistance to thyroid hormone beta with a novel THRB mutation; case reportRibbon diagrams of the predicted THRB structure from wild type (a) and p.E449DfsX11 mutant protein (b). The figures were produced with homology-based modeling using MOE. Red ribbons represent α-helices, and yellow arrows indicate the β-sheet. The mutated THRB has one different α-helix (amino acid number 450–451) (arrows)Back to article page