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Table 8 Multivariate analyses on height outcomes with GH 67 μg/kg/day and IGF variables available

From: Growth hormone (GH) dose-dependent IGF-I response relates to pubertal height gain

ITT

B

SEB

p

R2

Total gain in heightSDS

    

(Constant)

1.23

0.148

0.000

28

IGF-ISDS 1 year after GH start

0.24

0.058

0.000

 

∆IGF-ISDS pubertal level from study start

0.29

0.093

0.003

 

Pubertal gain in heightSDS

    

(Constant)

0.42

0.121

0.001

26

∆IGF-ISDS pubertal level from study start

0.34

0.086

0.000

 

∆IGF-I/IGFBP3 ratioSDS 1 year after GH start

0.20

0.063

0.002

 

Prepubertal gain in heightSDS

    

(Constant)

0.91

0.136

0.000

21

IGF-ISDS at GH start

−0.28

0.069

0.000

 
  1. Δ change, IGF-I insulin-like growth factor I, IGFBP3 IGF binding protein 3, SDS standard deviation score