Thyroid dysfunction and dyslipidemia in chronic kidney disease patients

BMC Endocrine Disorders

Table 3 Risk factors for thyroid dysfunction and cardiovascular disease in CKD

	Risk factors	Odds ratio (95 % CI)	P value
Thyroid dysfunction	Female gender	1.26 (0.82–1.92)	0.287
	Age > 60 years	1.53 (0.92–2.55)	0.098
	Diabetes mellitus	0.96 (0.63–1.48)	0.878
	CKD stage
	Stage 3	1 (reference)
	Stage 4	2.1 (1.28–3.42)	0.003
	Stage 5	3.64 (1.94–6.85)	<0.001
Cardiovascular disease	Hypertension	1.25 (0.79–1.97)	0.328
	Diabetes mellitus	1.93 (1.26–2.94)	0.002
	Hypercholesterolemia	4.95 (3.08–7.97)	<0.001
	Low HDL cholesterol	1.06 (0.68–1.64)	0.779
	Undesirable LDL cholesterol	2.83 (1.8–4.43)	<0.001
	CKD stage
	Stage 3	1 (reference)
	Stage 4	2.53 (1.57–4.08)	<0.001
	Stage 5	7.04 (3.55–13.97)	<0.001

Hypercholesterolemia, low HDL and undesirable LDL were considered if total cholesterol > 200 mg/dL, HDL cholesterol < 40 mg/dL and LDL cholesterol > 100 mg/dL respectively. Stage 3 CKD was considered as reference for calculating odds for thyroid dysfunction and CVD in stage 4 and stage 5 CKD

ISSN: 1472-6823