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Table 3 Risk factors for thyroid dysfunction and cardiovascular disease in CKD

From: Thyroid dysfunction and dyslipidemia in chronic kidney disease patients

  Risk factors Odds ratio (95 % CI) P value
Thyroid dysfunction Female gender 1.26 (0.82–1.92) 0.287
Age > 60 years 1.53 (0.92–2.55) 0.098
Diabetes mellitus 0.96 (0.63–1.48) 0.878
CKD stage
Stage 3 1 (reference)  
Stage 4 2.1 (1.28–3.42) 0.003
Stage 5 3.64 (1.94–6.85) <0.001
Cardiovascular disease Hypertension 1.25 (0.79–1.97) 0.328
Diabetes mellitus 1.93 (1.26–2.94) 0.002
Hypercholesterolemia 4.95 (3.08–7.97) <0.001
Low HDL cholesterol 1.06 (0.68–1.64) 0.779
Undesirable LDL cholesterol 2.83 (1.8–4.43) <0.001
CKD stage
Stage 3 1 (reference)  
Stage 4 2.53 (1.57–4.08) <0.001
Stage 5 7.04 (3.55–13.97) <0.001
  1. Hypercholesterolemia, low HDL and undesirable LDL were considered if total cholesterol > 200 mg/dL, HDL cholesterol < 40 mg/dL and LDL cholesterol > 100 mg/dL respectively. Stage 3 CKD was considered as reference for calculating odds for thyroid dysfunction and CVD in stage 4 and stage 5 CKD