From: Thyroid dysfunction and dyslipidemia in chronic kidney disease patients
Variables | All patients N = 360 | Stage 3 N = 144 | Stage 4 N = 156 | Stage 5 N = 60 | P value |
---|---|---|---|---|---|
Age (Years) | 44.1 ± 16.4 | 41.9 ± 16.1 | 47.5 ± 15.6 | 40.3 ± 17.7 | 0.002 |
Sex | |||||
Male | 53.8 % (194) | 18.8 % (68) | 25.2 % (91) | 9.7 % (35) | 0.117 |
Female | 46.1 % (166) | 21.1 % (76) | 18.0 % (65) | 6.9 % (25) | |
Diabetes mellitus | 45.8 % (165) | 18.3 % (66) | 17.5 % (63) | 10 % (36) | 0.035 |
Hypertension | 70.2 % (253) | 25.5 % (92) | 31.3 % (113) | 13.3 % (48) | 0.053 |
Cardiovascular disease | 46.9 % (169) | 11.9 % (43) | 22.5 % (81) | 12.5 % (45) | <0.001 |
Urea (mg/dL) | 106.3 ± 60.1 | 71.3 ± 39.5 | 100.7 ± 37.7 | 204.7 ± 39.5 | <0.001 |
Creatinine (mg/dL) | 4.0 ± 3.4 | 1.8 ± 0.3 | 3.3 ± 0.5 | 10.9 ± 3.2 | <0.001 |
eGFR (ml/min per 1.73 m2) | 28.2 ± 15.3 | 44.0 ± 8.9 | 22.0 ± 4.0 | 6.4 ± 2.6 | <0.001 |
Free T3 (pmol/L) | 4.9 ± 1.1 | 5.0 ± 1.1 | 4.9 ± 1.1 | 4.7 ± 0.8 | 0.131 |
Free T4 (pmol/L) | 11.6 ± 3.2 | 11.9 ± 3.2 | 11.5 ± 3.3 | 11.0 ± 2.6 | 0.175 |
TSH (mIU/L) | 3.2 (1.8, 6.8) | 2.5 (1.6, 4.3) | 3.3 (1.7, 7.3) | 5.4 (2.3, 8.8) | <0.001 |
Glucose (mg/dL) | 117.4 ± 44.6 | 119.9 ± 45.6 | 116.7 ± 46.7 | 113.0 ± 36.1 | 0.596 |
Total cholesterol (mg/dL) | 191.9 ± 31.7 | 194.2 ± 32.9 | 189.9 ± 31.3 | 191.6 ± 29.4 | 0.501 |
HDL cholesterol (mg/dL) | 42.1 ± 5.9 | 42.0 ± 5.8 | 42.0 ± 6.0 | 42.7 ± 6.1 | 0.718 |
LDL cholesterol (mg/dL) | 103.6 ± 28.1 | 106.1 ± 30.9 | 100.6 ± 25.6 | 105.0 ± 26.7 | 0.215 |
Triglyceride (mg/dL) | 205.7 ± 73.9 | 205.9 ± 79.8 | 207.1 ± 70.4 | 201.6 ± 68.8 | 0.884 |