Skip to main content

Table 1 Endocrine assessment at presentation before glucocorticoid initiation and two years after presentation

From: Clinical course of IgG4-related hypophysitis presenting with focal seizure and relapsing lymphocytic hypophysitis

Parameters

At presentationa (Normal value)

Two years after presentationb (Normal value)c

8 AM cortisol (μg/dL)

0.31 (3.7–19.4)

<0.40 (3.7–19.4)

Adrenocorticotropic hormone; ACTH (pg/mL)

<10 (0–71)

<1.6 (4.7–48.8)

Free triiodothyronine; FT3 (pg/mL)

1.71 (1.80–4.60)

Not done

Free thyroxine; FT4 (ng/dL)

0.25 (0.93–1.71)

0.59 (0.70–1.48)

Thyroid stimulating hormone; TSH (mIU/L)

1.990 (0.270–4.210)

1.962 (0.350–4.940)

Testosterone (ng/dL)

3 (280–300)

463 (280–300)

Follicle-stimulating hormone; FSH (mIU/mL)

2.10 (1.50–14.20)

<0.05 (0.95–11.95)

Lutheinizing hormone; LH (mIU/mL)

0.11 (1.70–8.60)

0 (0.57–12.07)

Insulin-like growth factor 1; IGF-1 (ng/mL)

77.50 (101.00–267.00)

96.41 (101.00–267.00)

Prolactin (ng/mL)

9.67 (4.04–15.20)

1.37 (3.46–19.40)

Peak serum cortisol after administration of 250 μg corticotropin (μg/dL)

4.19

Not done

Serum osmolarity (mOSm/kgH2O)

274 (275–295)

Not done

Urine osmolarity (mOSm/kgH2O)

625 (50–1400)

Not done

  1. aBefore steroid initiation
  2. bAll hormonal replacement and steroid were discontinued before laboratory assessment as follows: Prednisolone (3 days), Levothyroxine (1 week), and Testosterone enanthate (3 weeks)
  3. cNormal values were changed due to the Hospital laboratory was reorganized