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Table 4 Baseline characteristics of study participants, by presence of elevated depressive symptoms

From: Marginal structural models for the estimation of the risk of Diabetes Mellitus in the presence of elevated depressive symptoms and antidepressant medication use in the Women’s Health Initiative observational and clinical trial cohorts

 

Presence of elevated depressive symptoms

 

No

Yes

Total

No

Yes

Total

 

N (%)

N (%)

N (%)

N (%)

N (%)

N (%)

 

WHI-OS N = 68,169

WHI-CT N = 52,326

Antidepression medication usea

  No

54923 (94.1 %)

8457 (86.2 %)

63380 (93.0 %)

42582 (95.0 %)

6557 (87.4 %)

49139 (93.9 %)

  Yes

3440 (5.9 %)

1349 (13.8 %)

4789 (7.0 %)

2238 (5.0 %)

949 (12.6 %)

3187 (6.1 %)

Agea

      

  Mean(SD)

63.7 (7.2)

62.9 (7.5)

63.6 (7.3)

62.9 (6.9)

61.8 (7.1)

62.8 (6.9)

  Median(IQR)

64.0 (11.0)

63.0 (12.0)

64.0 (11.0)

63.0 (11.0)

61.0 (11.0)

63.0 (11.0)

Ethnicitya

      

  American Indian/Alaskan Native

172 (0.3 %)

55 (0.6 %)

227 (0.3 %)

151 (0.3 %)

38 (0.5 %)

189 (0.4 %)

  Asian or Pacific Islander

1839 (3.2 %)

214 (2.2 %)

2053 (3.0 %)

1124 (2.5 %)

105 (1.4 %)

1229 (2.4 %)

  Black/African American

3490 (6.0 %)

705 (7.2 %)

4195 (6.2 %)

3607 (8.1 %)

778 (10.4 %)

4385 (8.4 %)

  Hispanic/Latino

1478 (2.5 %)

513 (5.2 %)

1991 (2.9 %)

1313 (2.9 %)

483 (6.4 %)

1796 (3.4 %)

  White

50798 (87 %)

8196 (83.6 %)

58994 (86.5 %)

38158 (85.1 %)

6009 (80.1 %)

44167 (84.4 %)

Other

586 (1.0 %)

123 (1.3 %)

709 (1.0 %)

467 (1.0 %)

93 (1.2 %)

560 (1.1 %)

Educationa

      

  <= High school

1957 (3.4 %)

641 (6.6 %)

2598 (3.8 %)

1837 (4.1 %)

609 (8.2 %)

2446 (4.7 %)

  High school or GED

8784 (15.2 %)

1733 (17.8 %)

10517 (15.5 %)

8074 (18.1 %)

1504 (20.2 %)

9578 (18.4 %)

  > = High school, but less than 4 years of college

20643 (35.6 %)

3709 (38.2 %)

24352 (36.0 %)

17315 (38.9 %)

3031 (40.7 %)

20346 (39.1 %)

  4 or more years of college

26557 (45.8 %)

3631 (37.4 %)

30188 (44.6 %)

17330 (38.9 %)

2295 (30.9 %)

19625 (37.7 %)

BMIa

      

  Mean(SD)

26.7 (5.4)

27.6 (6.0)

26.8 (5.5)

28.4 (5.6)

29.3 (6.0)

28.5 (5.7)

  Median(IQR)

25.6 (6.3)

26.5 (7.1)

25.7 (6.4)

27.5 (7.1)

28.4 (7.7)

27.6 (7.2)

Minutes of recreational physical activity per weeka

   

  Mean(SD)

210.1 (186.6)

170.8 (175.7)

204.5 (185.6)

165.4 (168.7)

139.7 (165.5)

161.7 (168.5)

  Median(IQR)

170.0 (225.0)

127.5 (220.0)

165.0 (225.0)

125.0 (220.0)

85.0 (200.0)

120.0 (215.0)

Total energy intake (kcal/day)a

  Mean(SD)

1529.7 (588.9)

1593.2 (679.5)

1538.8 (603.2)

1710.7 (666.7)

1796.8 (762.7)

1723.0 (682.0)

  Median(IQR)

1461.9 (719.7)

1493.9 (817.1)

1465.4 (733.4)

1618.0 (815.0)

1671.6 (951.6)

1623.7 (833.7)

HRT use evera

      

  Never

16498 (28.8 %)

2663 (27.7 %)

19161 (28.6 %)

15945 (37.2 %)

2510 (34.9 %)

18455 (36.9 %)

  Former

11590 (20.2 %)

2209 (22.9 %)

13799 (20.6 %)

10805 (25.2 %)

2077 (28.9 %)

12882 (25.7 %)

  Current

29228 (51.0 %)

4758 (49.4 %)

33986 (50.8 %)

16099 (37.6 %)

2602 (36.2 %)

18701 (37.4 %)

Relative had adult diabetesa

  No

38718 (66.6 %)

6052 (62.0 %)

44770 (65.9 %)

28802 (64.5 %)

4502 (60.3 %)

33304 (63.9 %)

  Yes

17225 (29.6 %)

3161 (32.4 %)

20386 (30.0 %)

13867 (31.1 %)

2515 (33.7 %)

16382 (31.4 %)

Smoking statusa

      

  Never Smoked

29984 (52.0 %)

4818 (49.7 %)

34802 (51.6 %)

23382 (52.7 %)

3594 (48.4 %)

26976 (52.1 %)

  Past Smoker

24751 (42.9 %)

4141 (42.7 %)

28892 (42.9 %)

18012 (40.6 %)

3048 (41.1 %)

21060 (40.6 %)

  Current Smoker

2971 (5.1 %)

738 (7.6 %)

3709 (5.5 %)

3004 (6.8 %)

776 (10.5 %)

3780 (7.3 %)

Reported diagnosis of diabetes by end of follow-upa

  No

55407 (94.9%)

9138 (93.2%)

64545 (94.7%)

41399 (92.4%)

6756 (90.0%)

48155 (92.0%)

  Yes

2956 (5.1%)

668 (6.8%)

3624 (5.3%)

3421 (7.6%)

750 (10.0%)

4171 (8.0%)

Years from enrollment to development of diabetesa

   

  Mean(SD)

7.7 (1.5)

7.6 (1.6)

7.7 (1.5)

8.0 (1.7)

7.9 (1.8)

8.0 (1.7)

  Median(IQR)

7.9 (2.0)

7.9 (2.0)

7.9 (2.0)

8.0 (1.7)

8.0 (1.9)

8.0 (1.8)

  Don’t Know

2212 (3.8 %)

555 (5.7 %)

2767 (4.1 %)

1975 (4.4 %)

452 (6.1 %)

2427 (4.7 %)

  1. aP-value <0.007 or lower