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Table 4 Change in clinical and metabolic parameters, presented in all subjects as well as the subgroup that were normoglycaemic at baseline, stratified according to follow up glycemic tolerance status

From: Metabolic predictors of impaired glucose tolerance and type 2 diabetes in a predisposed population – A prospective cohort study

 

All

NGT-NGT

NGT-IGT/T2D

P-values

N

135

100

14

 

Delta BMI (kg/m2)

0.9 ± 2.0

0.7 ± 1.6

1,7 ± 2,3

0,0569

Delta weight (kg)

2.6 ± 6.3

1.9 ± 4.9

4.8 ± 7.1

0.062

Delta fat per cent (%)

0.6 ± 4.2

0.3 ± 4.1

3.4 ± 5.2

0.0203*

Delta fasting plasma glucose (mmol/L)

0.2 ± 1.1

0.1 ± 0.4

0.3 ± 0.6

n.s.

Delta OGTT 2 h plasma glucose (mmol/L)

0.5 ± 2.5

0.1 ± 1.1

2.8 ± 1.3

<0.0001***

Delta HbA1c (mmol/mol)

1.4 ± 6.8

0.5 ± 2.1

1.1 ± 1.7

n.s.

Delta serum triglycerides (mmol/L)

−0.1 ± 0.6

0.0 ± 0.7

−0.1 ± 0.4

n.s.

Delta serum cholesterol (mmol/L)

0.2 ± 0.8

0.2 ± 0.9

0.3 ± 1.1

n.s.

Delta serum HDL (mmol/L)

0.03 ± 0.3

0.05 ± 0.2

−0.1 ± 0.3

0.0858

Delta serum LDL (mmol/L)

0.2 ± 0.6

0.3 ± 0.6

0.4 ± 0.9

n.s.

  1. NGT = normal glucose tolerance. IGT = impaired glucose tolerance. T2D = type 2 diabetes mellitus. Data are means ± standard deviation. Delta values have been calculated subtracting the baseline value from the follow-up value of the same variable. P-values below 0.1 are given numerically, otherwise stated as not significant (n.s.)