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Table 3 Multiple logistic regression analyses of odds ratios for hyperfiltration

From: Association of elevated glycosylated hemoglobin A1c with hyperfiltration in a middle-aged and elderly Chinese population with prediabetes or newly diagnosed diabetes: a cross-sectional study

 

Fasting plasma glucose (per mmol/L)

HbA1c (per % unit)

 

OR

95 % CI

P value

 

OR

95 % CI

P value

Model 1

Fasting glucose, per mmol/L

0.947

(0.826-1.086)

0.434

HbA1c, per % unit

0.850

(0.689-1.048)

0.128

Q1 (<5.40)

1

  

Q1 (<5.70)

1

  

Q2 (5.40-5.70)

0.654

(0.482-0.887)

0.006

Q2 (5.70-6.00)

0.644

(0.443-0.936)

0.021

Q3 (5.71-6.30)

0.786

(0.499-0.919)

0.012

Q3 (6.01-6.20)

0.593

(0.405-0.870)

0.007

Q4 (6.31-6.99)

0.692

(0.338-0.994)

0.047

Q4 (6.21-6.49)

1.234

(0.992-2.719)

0.053

Q5 (≥7.0)

0.871

(0.689-1.698)

0.734

Q5 (≥6.5)

0.900

(0.583-1.390)

0.819

Model 2

Fasting glucose, per mmol/L

1.222

(1.064-1.405)

0.005

HbA1c, per % unit

1.301

(1.027-1.648)

0.029

Q1 (<5.40)

1

  

Q1 (<5.70)

1

  

Q2 (5.40-5.70)

0.820

(0.545-1.234)

0.341

Q2 (5.70-6.00)

0.779

(0.522-1.222)

0.300

Q3 (5.71-6.30)

0.884

(0.572-1.367)

0.579

Q3 (6.01-6.20)

0.876

(0.564-1.361)

0.557

Q4 (6.31-6.99)

1.181

(0.545-1.2.563)

0.673

Q4 (6.21-6.49)

2.497

(1.144-5.440)

0.025

Q5 (≥7.0)

3.719

(1.969-7.024)

<0.001

Q5 (≥6.5)

2.424

(1.315-4.469)

0.005

Model 3

Fasting glucose, per mmol/L

1.306

(1.117-1.526)

0.001

HbA1c, per % unit

1.396

(1.089-1.790)

0.008

Q1 (<5.40)

1

  

Q1 (<5.70)

1

  

Q2 (5.40-5.70)

0.845

(0.547-1.305)

0.448

Q2 (5.70-6.00)

0.968

(0.623-1.504)

0.885

Q3 (5.71-6.30)

1.144

(0.731-1.791)

0.557

Q3 (6.01-6.20)

0.945

(0.598-1.496)

0.811

Q4 (6.31-6.99)

2.369

(1.255-4.473)

0.097

Q4 (6.21-6.49)

2.344

(1.025-5.364)

0.044

Q5 (≥7.0)

4.889

(2.454-9.739)

<0.001

Q5 (≥6.5)

2.965

(1.537-5.720)

<0.001

  1. Model 1: not adjusted; Model 2: adjusted for age, gender, waistline, body mass index, systolic blood pressure and diastolic blood pressure; Model 3: Model 2 plus adjustment for cholesterol, Log (triglyceride), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, serum uric acid, alcohol consumption, smoking status, sodium, hypertension, and use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers. 95 % CI, 95 % confidence interval; HbA1c, glycated hemoglobin; OR, odds ratio