Association of elevated glycosylated hemoglobin A1c with hyperfiltration in a middle-aged and elderly Chinese population with prediabetes or newly diagnosed diabetes: a cross-sectional study

Table 2 Multiple linear regression analysis of the relationship between HbA1c and eGFR

	Fasting plasma glucose (per mmol/L)			HbA1c (per % unit)
	b Coefficient	95 % CI	P value	b Coefficient	95 % CI	P value
Model 1	−0.466	(−1.037, −0.087)	0.015	−0.471	(−1.363, 0.078)	0.203
Model 2	0.424	(−0.016, 0.864)	0.059	1.044	(0.378, 1.711)	0.002
Model 3	0.761	(0.340, 1.180)	<0.001	1.259	(0.625, 1.892)	<0.001

Model 1: not adjusted; Model 2: adjusted for age, gender, waistline, body mass index, systolic blood pressure and diastolic blood pressure; Model 3: Model 2 plus adjustment for cholesterol, Log (triglyceride), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, serum uric acid, alcohol consumption, smoking status, sodium intake (6 g/day), hypertension, and use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers. 95 % CI, 95 % confidence interval; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin

ISSN: 1472-6823