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Table 2 β Cell function and Insulin Sensitivity of newly diagnosed T2DM with different levels of TG

From: Clinical characteristics and beta cell function in Chinese patients with newly diagnosed type 2 diabetes mellitus with different levels of serum triglyceride

  Group1 (0-25%) Group2 (25%-50%) Group3 (50%-75%) Group4 (75%-100%)
β Cell Function  
HOMA-β 47.83 (32.62, 71.70) 55.03 (35.28, 86.35) 66.14 (36.47, 95.63)* 52.39 (31.42, 82.52)+
MBCI 2.76 (1.67, 3.77) 3.33 (2.13, 5.26)* 3.19 (2.38, 5.46)* 3.59 (2.32, 5.13)*
IGI 2.39 (1.14, 4.78) 2.79 (0.93, 5.60) 3.40 (1.09, 8.14) 2.81 (0.82, 6.02)
DI 1.05 (0.44, 1.96) 0.97 (0.32, 1.94) 1.08 (0.32, 2.49) 0.84 (0.25, 1.83)
Insulin Sensitivity  
HOMA-IR 2.49 (1.70, 3.59) 3.06 (2.10, 4.62)* 3.05 (2.22, 4.86)* 3.15 (2.41, 4.87)*
IAI 0.0178 (0.012, 0.026) 0.0145 (0.010, 0021)* 0.0146 (0.010, 0.020)* 0.0141 (0.010, 0.019)*
  1. Data were expressed as median (Interquartile range 25-75%) for skewed variables.
  2. HOMA-β: homeostasis model assessment of β cell function; MBCI: modified beta cell function index; IGI: early insulin secretion function index; DI: glucose disposition indices; HOMA-IR: homeostasis model assessment of insulin resistance; IAI: insulin action index; T2DM: type 2 diabetes mellitus.
  3. Group was defined by the quartile of serum TG. Group 1: newly diagnosed T2DM with TG up to 1.13 mmol/L; Group 2: newly diagnosed T2DM with TG of 1.14 to 1.56 mmol/L; Group 3: newly diagnosed T2DM with TG of 1.57 to 2.27 mmol/L; and Group 4: newly diagnosed T2DM with TG of 2.28 to 11.65 mmol/L.
  4. *P < 0.05 versus Group 1; #P < 0.05 versus Group 2; +P < 0.05 versus Group 3.