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Table 2 β Cell function and Insulin Sensitivity of newly diagnosed T2DM with different levels of TG

From: Clinical characteristics and beta cell function in Chinese patients with newly diagnosed type 2 diabetes mellitus with different levels of serum triglyceride

 

Group1 (0-25%)

Group2 (25%-50%)

Group3 (50%-75%)

Group4 (75%-100%)

β Cell Function

 

HOMA-β

47.83 (32.62, 71.70)

55.03 (35.28, 86.35)

66.14 (36.47, 95.63)*

52.39 (31.42, 82.52)+

MBCI

2.76 (1.67, 3.77)

3.33 (2.13, 5.26)*

3.19 (2.38, 5.46)*

3.59 (2.32, 5.13)*

IGI

2.39 (1.14, 4.78)

2.79 (0.93, 5.60)

3.40 (1.09, 8.14)

2.81 (0.82, 6.02)

DI

1.05 (0.44, 1.96)

0.97 (0.32, 1.94)

1.08 (0.32, 2.49)

0.84 (0.25, 1.83)

Insulin Sensitivity

 

HOMA-IR

2.49 (1.70, 3.59)

3.06 (2.10, 4.62)*

3.05 (2.22, 4.86)*

3.15 (2.41, 4.87)*

IAI

0.0178 (0.012, 0.026)

0.0145 (0.010, 0021)*

0.0146 (0.010, 0.020)*

0.0141 (0.010, 0.019)*

  1. Data were expressed as median (Interquartile range 25-75%) for skewed variables.
  2. HOMA-β: homeostasis model assessment of β cell function; MBCI: modified beta cell function index; IGI: early insulin secretion function index; DI: glucose disposition indices; HOMA-IR: homeostasis model assessment of insulin resistance; IAI: insulin action index; T2DM: type 2 diabetes mellitus.
  3. Group was defined by the quartile of serum TG. Group 1: newly diagnosed T2DM with TG up to 1.13 mmol/L; Group 2: newly diagnosed T2DM with TG of 1.14 to 1.56 mmol/L; Group 3: newly diagnosed T2DM with TG of 1.57 to 2.27 mmol/L; and Group 4: newly diagnosed T2DM with TG of 2.28 to 11.65 mmol/L.
  4. *P < 0.05 versus Group 1; #P < 0.05 versus Group 2; +P < 0.05 versus Group 3.
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BMC Endocrine Disorders

ISSN: 1472-6823

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