High prevalence of metabolic syndrome in a mestizo group of adult patients with primary hyperparathyroidism (PHPT)

Table 2 Baseline clinical and biochemical characteristics of patients with PHPT with and without MS

	With MS	Without MS	p
Age (y), mean ± SD	57.2 ± 12.6	48 ± 14.2	0.014^a
Female, n (%)	27 (75)	19 (79)	0.78
Weight (kg), median (IR)	73 (63–85)	63.5 (54–71)	0.010^b
Height (m), mean ± SD	1.57 ± 0.09	1.56 ± 0.09	0.65
BMI (kg/m ² ), mean ± SD	30.3 ± 4.58	27.1 ± 5.02	0.017^a
Glucose (mg/dl), median (IR)	107 (96.7-126.5)	90 (84.5-102.7)	0.006^b
Calcium (mg/dl), mean ± SD	10.8 ± 0.93	11.43 ± 1.25	0.07^a
Phosphorus (mg/dl), mean ± SD	3.2 ± 0.60	2.9 ± 0.77	0.114
iPTH (ng/ml), median (IR)	115 (73.6-154.2)	161.5 (100.9-231.5)	0.017^b
Triglycerides (mg/dl), median (IR)	231.5 (168.7-289.5)	133 (113.7-178.2)	<0.001^b
c-HDL (mg/dl), mean ± SD
Female
Male	46.19 ± 12.6	52.42 ± 11.08	0.090
Male	41.78 ± 11.14	44.6 ± 4.72	0.604
Central obesity, n (%)	30(83)	7(29)	<0.001^c
Hypertension, n(%)	21(58)	3(12.5)	<0.001^c
Hypertriglyceridemia, n(%)	32(89)	9(38)	<0.001^c
Low c-HDL concentration (%)	23(64)	8(33)	0.019^c
Impairment of glucose metabolism, n(%)	28(78)	8(33)	0.001^c
T2DM, n(%)	16(44)	2(8)	0.002^c

Abbreviations: BMI = body mass index, T2DM = type 2 diabetes mellitus, IR = interquartile range, iPTH = intact parathyroid hormone. ^aStudent t test, ^bMann–Whitney U test, ^cFisher’s exact test.

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