Low-dose combined oral contraceptive use is associated with lower bone mineral content variation in adolescents over a 1-year period

Table 2 Comparison of variations in DXA between the control group and COC users at baseline and after 12 months

Variable	Non COC			COC users			Difference⁽¹⁾	P
Variable	Initial	Final	Variation (%)	Initial	Final	Variation (%)	Difference⁽¹⁾	P
Lumbar BMD (g/cm²)	0.854	0.958	12.16	0.959	0.949	2.07	10.09	0.056
Lumbar BMC (g)	46.37	53.73	16.84	49.82	49.03	1.57	15.27	0.014
Subtotal BMD (g/cm²)	0.879	0.903	5.28	0.874	0.869	0.56	4.72	0.149
Subtotal BMC (g)	1320.18	1538.46	16.04	1407.01	1414.69	1.18	14.86	0.033
Whole body BMD (g/cm²)	1.003	1.042	5.28	0.995	0.992	0.84	4.44	0.149
Whole body BMC (g)	1783.62	2006.98	11.34	1831.42	1849.58	1.22	10.12	0.031

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