Table 1 Baseline characteristics of 1,326 patients presented as quartiles NT-proSST concentration
All patients | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P-value | |
|---|---|---|---|---|---|---|
NT-proSST (pmol/L) | 592 [450–783] | <450 | 450-590 | 590-780 | >780 | |
N | 1326 | 332 | 330 | 332 | 332 | |
Deceased (N,%) | 413 (31) | 73 (22) | 74 (22) | 115 (35) | 151 (46) | |
Follow-up time (years) | 6 [3-10] | 6 [3-10] | 9 [3-10] | 7 [3-10] | 5 [3-10] | |
Female sex (N,%) | 738 (56) | 155 (34) | 182 (55) | 198 (60) | 203 (61) | <0.01 |
Age (years) | 70 [61–76] | 62 [52–72] | 65 [58–72] | 69 [61–77] | 73 [65–78] | <0.01 |
Smoking (%) | 19.0 | 13 | 16 | 13 | 13 | 0.28 |
History of CVD (%) | 34 | 26 | 33 | 37 | 42 | <0.01 |
Diabetes duration (years) | 4 [2–9] | 3.1 [2–8] | 4 [2–9] | 5 [2–10] | 5 [2–10] | <0.01 |
BMI (kg/m2) | 28 [25–32] | 30 [27–33] | 29 [26–32] | 29 [25–32] | 28 [25–30] | <0.01 |
SBP (mmHg) | 150 [140–170] | 150 [135–162] | 150 [135–170] | 150 [140–170] | 150 [135–170] | 0.29 |
HbA1c (%) | 7.0 [6.3 - 8.0] | 7.1 [6.3 - 8.3] | 7.0 [6.2 – 8.1] | 7.0 [6.4 - 8.0] | 7.0 [6.3 - 8.0] | 0.83 |
HbA1c (mmol/mol) | ||||||
Serum creatinine (μmol/L) | 92 [82–104] | 86 [77–94] | 89 [80–100] | 93 [84–105] | 102 [89–199] | <0.01 |
Cholesterol:HDL ratio | 4.8 [3.9 - 6.0] | 4.8 [3.9 - 5.7] | 4.8 [4.0 - 5.7] | 4.7 [3.9 - 6.1] | 4.8 [3.8 - 5.9] | 0.68 |
Albuminuria present (N,%) | 515 (39) | 129 (39) | 106 (32) | 130 (39) | 150 (45) | <0.01 |