Table 1 Anthropometric, metabolic and biochemical parameters at baseline and after treatment with liraglutide

Weight (kg)

102.1 (17.1)

100.4 (15.1)

−3.0^†

−3.8^†

−1.9 – 3.4

0.56

BMI (kg/m²)

37.9 (5.0)

36.5 (4.6)

−1.0^†

−1.4^†

−0.6 – 1.3

0.43

Waist (cm)

112.0 (12.6)

112.3 (9.7)

−1.1

−1.4

−2.4 – 3.2

0.78

Systolic BP (mmHg)

121 ± 13.0

126 ± 12.9

0.0

−4.4

−2.9 – 11.7

0.23

Diastolic BP (mmHg)

75 (7.6)

79 (6.6)

0.3

−3.9

−2.1 – 10.4

0.19

Average HR (bpm)

67.7 (7.7)

67.3 (9.0)

3.0

4.0^†

−5.0 – 4.0

0.77

Metabolic syndrme

10 (52.6%)

6 (35.3%)

−4.0

0.0

Testosterone (nmol/L)

1.3 (0.4)

0.90 (0.3)*

−0.03

0.04

−0.4 – 0.2

0.63

FAI

4.4 (2.0)

2.6 (1.2)*

0.09

−0.06

−1.2 – 1.5

0.76

SHBG (nmol/L)

33.2 (14.6)

38.1 (14.4)

−2.4

2.3

−10.9 – 1.7

0.50

FPG (mmol/L)

5.1 (0.6)

4.9 (0.4)

−0.2^†

−0.3^†

−0.2 – 0.4

0.40

Insulin (iu/ml)

22.0 (9.4)

16.1 (5.6)*

−2.6^†

−3.4^†

−2.3 – 3.9

0.61

HOMA-IR

5.1 (2.6)

3.5 (1.3)*

−0.8^†

−0.9*

−0.6 – 0.9

0.70

HOMA-β

303 (135)

255 (114)

11.2

10.7

−70.0 – 70.9

1

hsCRP (mg/L)

6.2 (8.7)

5.1 (3.4)

−1.9^†

−1.2^†

−4.3 – 2.9

0.21

Total chol (mmol/L)

5.0 (0.8)

5.1 (1.0)

−0.1

−0.02

−0.4 – 0.3

0.64

LDL (mmol/L)

3.2 (0.6)

3.3 (0.9)

0.06

0.08

−0.3 – 0.3

0.89

HDL (mmol/L)

1.2 (0.2)

1.3 (0.2)

−0.02

−0.04

−0.1 – 0.2

0.84

Tri (mmol/L)

1.4 (0.7)

1.4 (0.7)

−0.3^†

−0.2^†

−0.4 – 0.2

0.56

Chol/HDL

4.4 (0.9)

4.1 (0.8)

−0.03

0.1

−0.6 – 0.3

0.37

Isoprostane (ng/ml)

0.81 (0.53)

0.58 (0.57)

−0.5^†

−0.4^†

−0.5 – 0.3

0.64

Fibrinogen (mg/ml)

3.8 (1.2)

3.5 (1.0)

0.02

−0.03

−0.4 – 0.5

0.84

cIMT

0.51 (0.05)

0.48 (0.06)

0.002

0.004

−0.01 – 0.02

0.41

RHI

1.9 (0.5)

1.9 (0.5)

−0.01

0.1

−0.8 – 0.6

0.68

sP-selectin (ng/ml)

135.9 (40.3)

126.4 (25.5)

−36.4^†

−47.1^†

−13.7 – 35.1

0.38

sICAM-1 (ng/ml)

302.8 (53.3)

302.1 (36.9)

−53.6^†

−78.2^†

−16.8 – 66.0

0.24

sVCAM-1 (ng/ml)

3384 (379)

3449 (404)

−1600^†

−1824^†

−335 – 782

0.42