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Figure 4 | BMC Endocrine Disorders

Figure 4

From: Activation of κ-opioid receptor by U50,488H improves vascular dysfunction in streptozotocin-induced diabetic rats

Figure 4

U50,488H increased serum NO levels and reduced ANG II levels in DM rats. (A) ELISA analysis showed significant decreases in serum NO levels in DM rats as compared with CON group. Treatment with U50,488H increased NO levels in DM. (B) ELISA analysis showed significant increases in serum ANG II levels in DM rats as compared with CON group, and U50,488H treatment blocked this elevation. (C) eNOS phosphorylation in DM rats was decreased in DM group and markedly increased after U50,488H treatment. *P < 0.05 vs. CON group, #P < 0.05 vs. DM group. (n = 5).

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BMC Endocrine Disorders

ISSN: 1472-6823

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