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Table 5 Induction of apoptosis/necrosis in INS-1E-ZnT8-EGFP cells relative to INS-1E cells following cytokine exposure (n = 3).

From: Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

 

IL-1β/12 h

IL-1β/24 h

IL-1β/36 h

Mix/12 h

Mix/24 h

Mix/36 h

Apoptosis

-

*4.1 +/- 0.21

*1.8 +/- 0.23

-

-

-

Necrosis

-

-

-

-

-

-

  1. Data represent mean of two independent experiments. Fold changes between cell lines are indicated. (*) p < 0.05 in both experiments. Only significant changes are shown +/- SEM. Mix. is IL-1β+TNF-α+IFN-γ IL-1β.
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BMC Endocrine Disorders

ISSN: 1472-6823

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