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Table 1 Comparison between before and after GH treatment

From: Factors influencing the growth hormone peak and plasma insulin-like growth factor I in young adults with pituitary stalk interruption syndrome

Groups (n)

Isolated GH deficiency (9)

P

Multiple pituitary deficiencies (12)

P

 

at diagnosis

at last evaluation

 

at diagnosis

at last evaluation

 

Height, SDS

-3.0 ± 1.0

-1.0 ± 0.9

<0.008

-3.1 ± 1.6

-0.9 ± 0.7

<0.004

BMI, SDS

-0.3 ± 1.2

0.6 ± 1.4

0.03

0.4 ± 2.4

0.6 ± 1.7

NS

GH peak, ng/ml

3.8 ± 1.9

3.9 ± 1.9

NS

1.6 ± 1.5a

0.2 ± 0.4b

<0.008

IGF I, SDS

-4.1 ± 0.9

-3.2 ± 1.2

NS

-4.4 ± 0.9

-5.0 ± 0.9c

NS

Testosterone, ng/ml

 

5.3 ± 1.8

  

1.7 ± 2.0

 
  1. Mean ± SD
  2. Isolated GH deficiency compared to multiple pituitary deficiencies: a: P < 0.02; b: P = 0.0001; c: P < 0.002