Groups (n) | Isolated GH deficiency (9) | P | Multiple pituitary deficiencies (12) | P | ||
---|---|---|---|---|---|---|
at diagnosis | at last evaluation | at diagnosis | at last evaluation | |||
Height, SDS | -3.0 ± 1.0 | -1.0 ± 0.9 | <0.008 | -3.1 ± 1.6 | -0.9 ± 0.7 | <0.004 |
BMI, SDS | -0.3 ± 1.2 | 0.6 ± 1.4 | 0.03 | 0.4 ± 2.4 | 0.6 ± 1.7 | NS |
GH peak, ng/ml | 3.8 ± 1.9 | 3.9 ± 1.9 | NS | 1.6 ± 1.5a | 0.2 ± 0.4b | <0.008 |
IGF I, SDS | -4.1 ± 0.9 | -3.2 ± 1.2 | NS | -4.4 ± 0.9 | -5.0 ± 0.9c | NS |
Testosterone, ng/ml | 5.3 ± 1.8 | 1.7 ± 2.0 |