| | AST | ALT | GGT |
|---|
| | Odds ratio | P | Odds ratio | P | Odds ratio | P |
|---|
Model 1 | 1.96(0.64–5.95) | 0.2 |
3.07(1.21–7.79)
|
0.01
|
2.91(1.29–6.53)
|
0.01
|
Model 2 | 1.27(0.47–3.42) | 0.5 |
3.62(1.37–9.53)
|
0.009
|
2.70(1.15–6.35)
|
0.02
|
Model 3 | 1.56 (0.42–5.74) | 0.5 |
3.32(1.18–9.30)
|
0.02
|
3.23 (1.32–7.92)
|
0.01
|
Model 4 | 1.09(0.34–3.53) | 0.8 |
3.18(1.02–9.86)
|
0.04
| 1.93(0.73–5.04) | 0.1 |
- AST: Aspartate aminotransferase, ALT: Alanin aminotransferase, GGT: Gamma glutamyltransferase
- *All the hepatic markers were log transformed before analysis. Odds ratios were calculated using backward conditional logistic regression with standardization to a SD of 1. Factor scores obtained from factor analysis were considered as continuous independent variables. In model 1 only the individual hepatic markers were entered (univariate). Model 2 was adjusted for log transformed C-reactive protein and HOMA-IR. Model 3 was further adjusted for family history of diabetes as well as anthropometric (waist circumference, waist-to-hip ratio and body mass index) and blood pressure (systolic and diastolic blood pressure and 2-hours glucose) factor scores. Model 4 was adjusted for all the variables in model 3 plus metabolic (Fasting and 2-hours glucose, triglycerides and HDL-cholesterol) factor score.
