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Table 3 Indices of glucose m etabolism and oxidative stress from serum and skeletal m uscle sam ples, as well as m axim al oxygen uptake in the subjects with im paired glucose tolerance (IGT) divided into two muscle phenotype groups.

From: Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose tolerance

  IGTslow subjects Baseline 2-year follow-up IGTfast subjects Baseline 2-year follow-up
n = (Female/Male) 10 (4/6) 12 (2/10)
Serum     
HbA1c, % 5.74 ± 0.13 5.38 ± 0.08* 5.67 ± 0.11 5.33 ± 0.14**
HOM A-IR 3.52 ± 0.30 3.22 ± 0.51 5.23 ± 0.75 3.77 ± 0.71*
ORAC, μmol 56.0 ± 4.5 58.2 ± 3.1 54.0 ± 3.4 55.4 ± 3.2
P. carbonyl, arb.u. 0.129 ± 0.005 0.126 ± 0.00 0.110 ± 0.003## 0.106 ± 0.003* ##
Uric acid, μmol/l 370 ± 17 331 ± 18** 379 ± 17 342 ± 21*
Skeletal muscle     
P. carbonyl, arb.u. 0.074 ± 0.011 0.071 ± 0.008 0.072 ± 0.007 0.070 ± 0.005
4-HNE, arb.u. 0.29 ± 0.07 0.24 ± 0.04 0.25 ± 0.04 0.26 ± 0.04
Maximal oxygen uptake     
VO2max, l/min 1.96 ± 0.22a 2.10 ± 0.20* a 2.52 ± 0.15 2.69± 0.15**
VO2max, /weight ml/kg/min 23.3 ± 2.7a 25.3 ± 2.4* a 28.2 ± 1.7 30.9 ± 1.6**
  1. Data are given as means ± SE; *P < 0.05, ** P < 0.01 within group; # P < 0.05, ## P < 0.01 between groups;a n = 9.