The role of selenium, vitamin C, and zinc in benign thyroid diseases and of selenium in malignant thyroid diseases: Low selenium levels are found in subacute and silent thyroiditis and in papillary and follicular carcinoma

Table 4 One-way ANOVA (Bonferroni) analysis of the Se levels

	n	mean	S.D.	SEM	95% confidence interval		minimum	maximum	p-value vs controls
					low	high
Controls	554	90,49	20,85	0,89	88,75	92,23	47,34	187,20
Ski jumpers	24	83,17	26,51	5,41	71,97	94,36	51,30	136,00	1
Ski runners	109	86,59	21,04	2,02	82,60	90,59	45,82	165,00	1
Children hypothyroidism	47	81,98	22,53	3,29	75,36	88,59	41,30	131,00	1
Children Hashimoto	28	77,40	23,54	4,45	68,27	86,53	40,50	119,30	0,308
Children hyperthyroidism	4	65,95	13,99	6,99	43,69	88,21	53,40	81,00	1
Children polyendocrinopathy	6	66,93	20,92	8,54	44,98	88,89	43,70	96,20	1
Thyroid normal adults	283	81,06	21,62	1,29	78,53	83,59	30,10	172,80	< 0,001
Thyroid immunogenic adults	131	81,98	24,82	2,17	77,69	86,27	28,50	163,00	0,009
Subacute thyroiditis adults	25	66,35	23,13	4,63	56,81	75,90	31,30	119,40	< 0,001
Silent thyroiditis adults	26	59,28	20,13	3,95	51,15	67,42	20,70	96,90	< 0,001
anaplastic Ca	3	95,00	13,25	7,65	62,08	127,92	87,35	110,30	1
follicular Ca	42	76,89	21,16	3,26	70,30	83,49	47,38	124,00	0,015
foll papillary Ca	11	68,85	18,57	5,60	56,37	81,33	46,84	96,77	0,176
giant cell papillary Ca	10	83,69	26,88	8,50	64,46	102,91	51,10	113,40	1
invasive Ca	8	74,80	18,28	6,46	59,51	90,08	60,68	103,10	1
microcarcinoma	4	68,10	9,54	4,77	52,91	83,28	59,83	76,36	1
papillary Ca	73	80,40	19,87	2,33	75,77	85,04	50,72	121,80	0,031
unclassified Ca	13	75,91	20,72	5,75	63,38	88,43	47,38	110,30	1
All	1401	84,20	22,50	0,60	83,02	85,38	20,70	187,20

ISSN: 1472-6823