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Table 6 Comparison of our fT4 reference intervals to previously published reference intervals (2.5, 50 and 97.5%) of different age groups.

From: Pediatric reference intervals for thyroid hormone levels from birth to adulthood: a retrospective study

   Soldin et al., 1995 Abbott IMx® Zurakowski et al., 1999 DELFIA® Elmlinger et al., 2001 Immulite® Djemli et al., 2004 Access 2® Hübner et al., 2002 Advia Centaur® Kapelari et al. Advia Centaur®
  Age       
fT4   [pmol/L] [pmol/L] [pmol/L] [pmol/L] [pmol/L] [pmol/L]
   n = 1,173 n = 353 n = 762 n = 710 n = 460 n = 1,221
  1d – 7d F: 11 – 25 n.d. 29.60 – 62.40 – 79.20 F: 11.0 – 13.6 – 22.3 10.8 – 26.8 a 8.54 – 20.10 – 30.20
   M: 10 – 36      
  8 – 15 d F: 8 – 25 n.d. 18.00 – 42.30 – 63.60 M: 9.8 – 12.2 – 23.2 10.9 – 25.5 b  
  15 d – 1 m M: 6 – 30 n.d. n.d.    
  1 – 12 m F: 11 – 24 9.5 – 19.5 – 39.5 11.10 – 19.70 – 27.30 F: 9.0 – 11.3 – 16.1 11.4 – 14.5 – 20.9 c 11.95 – 15.50 – 22.51
   M: 10 – 26      
  1 – 2 y     M: 8.7 – 11.7 – 16.2   
  2 – 3 y F: 13 – 22 9.0 – 18.4 – 37.2   n.d. 11.4 – 14.7 – 19.0 11.90 – 15.70 – 20.85
  3 – 4 y M: 12 – 21    n.d.   
  4 – 5 y    12.90 – 17.30 – 23.90 n.d.   
  5 – 6 y     n.d.   
  7 – 8 F: 11 – 20 8.3 – 16.9 – 34.1 12.90 – 19.30 – 24.50 n.d. 11.0 – 14.2 – 18.8 11.54 – 15.90 – 19.96
  9 – 10 M: 10 – 22   10.30 – 17.00 – 23.80 F: 9.6 – 11.6 – 14.5   
      M: 9.7 – 11.7 – 14.2   
  11    11.80 – 16.70 – 22.65    
  12 F: 10 – 19   10.40 – 16.20 – 22.91 F: 8.8 – 10.7 – 13.5 10.8 – 13.6 – 18.7 11.10 – 15.20 – 20.00
  13 M: 12 – 20 7.6 – 15.5 – 31.5 8.50 – 16.50 – 22.52 M: 8.4 – 10.8 – 13.0   
  14    12.20 – 16.50 – 23.30    
  15    9.10 – 17.00 – 23.40   10.7 – 14.4 – 18.7 10.80 – 15.20 – 20.33
  16 F: 11 – 19   12.90 – 16.70 – 23.30 F: 8.7 – 10.7 – 13.6   
  17 M: 12 – 20 7.0 – 14.1 – 28.7 11.80 – 17.40 – 22.50 M: 9.5 – 11.8 – 15.0   
  18 – 19    9.30 – 14.50 – 20.50 n.d.   
  1. a 1 d – 3 d
  2. b 4 d – 30 d
  3. c 61 d
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