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Table 6 Comparison of our fT4 reference intervals to previously published reference intervals (2.5, 50 and 97.5%) of different age groups.

From: Pediatric reference intervals for thyroid hormone levels from birth to adulthood: a retrospective study

  

Soldin et al., 1995 Abbott IMx®

Zurakowski et al., 1999 DELFIA®

Elmlinger et al., 2001 Immulite®

Djemli et al., 2004 Access 2®

Hübner et al., 2002 Advia Centaur®

Kapelari et al. Advia Centaur®

 

Age

      

fT4

 

[pmol/L]

[pmol/L]

[pmol/L]

[pmol/L]

[pmol/L]

[pmol/L]

  

n = 1,173

n = 353

n = 762

n = 710

n = 460

n = 1,221

 

1d – 7d

F: 11 – 25

n.d.

29.60 – 62.40 – 79.20

F: 11.0 – 13.6 – 22.3

10.8 – 26.8 a

8.54 – 20.10 – 30.20

  

M: 10 – 36

     
 

8 – 15 d

F: 8 – 25

n.d.

18.00 – 42.30 – 63.60

M: 9.8 – 12.2 – 23.2

10.9 – 25.5 b

 
 

15 d – 1 m

M: 6 – 30

n.d.

n.d.

   
 

1 – 12 m

F: 11 – 24

9.5 – 19.5 – 39.5

11.10 – 19.70 – 27.30

F: 9.0 – 11.3 – 16.1

11.4 – 14.5 – 20.9 c

11.95 – 15.50 – 22.51

  

M: 10 – 26

     
 

1 – 2 y

   

M: 8.7 – 11.7 – 16.2

  
 

2 – 3 y

F: 13 – 22

9.0 – 18.4 – 37.2

 

n.d.

11.4 – 14.7 – 19.0

11.90 – 15.70 – 20.85

 

3 – 4 y

M: 12 – 21

  

n.d.

  
 

4 – 5 y

  

12.90 – 17.30 – 23.90

n.d.

  
 

5 – 6 y

   

n.d.

  
 

7 – 8

F: 11 – 20

8.3 – 16.9 – 34.1

12.90 – 19.30 – 24.50

n.d.

11.0 – 14.2 – 18.8

11.54 – 15.90 – 19.96

 

9 – 10

M: 10 – 22

 

10.30 – 17.00 – 23.80

F: 9.6 – 11.6 – 14.5

  
     

M: 9.7 – 11.7 – 14.2

  
 

11

  

11.80 – 16.70 – 22.65

   
 

12

F: 10 – 19

 

10.40 – 16.20 – 22.91

F: 8.8 – 10.7 – 13.5

10.8 – 13.6 – 18.7

11.10 – 15.20 – 20.00

 

13

M: 12 – 20

7.6 – 15.5 – 31.5

8.50 – 16.50 – 22.52

M: 8.4 – 10.8 – 13.0

  
 

14

  

12.20 – 16.50 – 23.30

   
 

15

  

9.10 – 17.00 – 23.40

 

10.7 – 14.4 – 18.7

10.80 – 15.20 – 20.33

 

16

F: 11 – 19

 

12.90 – 16.70 – 23.30

F: 8.7 – 10.7 – 13.6

  
 

17

M: 12 – 20

7.0 – 14.1 – 28.7

11.80 – 17.40 – 22.50

M: 9.5 – 11.8 – 15.0

  
 

18 – 19

  

9.30 – 14.50 – 20.50

n.d.

  
  1. a 1 d – 3 d
  2. b 4 d – 30 d
  3. c 61 d
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BMC Endocrine Disorders

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