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Table 8 Serious clinical adverse experiences irrespective of relationship to study drug that occurred at an incidence rate of ≥0.2% in any group

From: Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis

 

Sitagliptin 100 mg

n (%)

(N = 3415)

Non-Exposed

n (%)

(N = 2724)

Difference between Sitagliptin

and Non-Exposed

% (95% CI)*

Coronary Artery Disease

5 (0.1)

7 (0.3)

-0.1 (-0.4, 0.1)

Myocardial Infarction

4 (0.1)

5 (0.2)

-0.1(-0.3, 0.1)

Non-cardiac Chest Pain

4 (0.1)

9 (0.3)

-0.2 (-0.5, 0.0)

Cholelithiasis

6 (0.2)

2 (0.1)

0.1 (-0.1, 0.3)

Pneumonia

4 (0.1)

5 (0.2)

-0.1 (-0.3, 0.1)

  1. CI = confidence interval
  2. *Positive differences indicate that the incidence rate for the sitagliptin group is higher than the incidence rate for the non-exposed group. "0.0" and "-0.0" represent rounding for values that are slightly greater and slightly less than zero, respectively.