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Table 5 Schedule of evaluation points

From: The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome

  EP 1.0 EP 1.1 EP 1.2 EP 1.3 EP 1.999
  Screening After 24 hours After 72 hours Weekly After discharge
Screening      
Inclusion and Exclusion criteria    
Informed consent    ° ° °
Demography      
Age, Gender     
History     
Laboratory examinations      
TSH, TT4, FT4, TT3, FT3   
rT3     
Total protein, Albumin   
BC, CRP, ATIII, Fibrinogen   
Thyroid antibodies, T4/T3-Abs.     
Other investigations   
Temperature, Horowitz-Quotient      
Vital signs  
Evolution data      
Medication
APACHE-II-/SAPS-II-Score, GCS  
Diagnosis    
HD/CVVH/CVVHDF
IABP
Persistent organ failure     
Outcome (survival etc.)     
  EP 2.0 EP 2.1 EP 2.2 EP 2.3  
  After transfer to peripheral ward After 3 months After 6 months After 1 year  
History and clinical data      
Burch-Wartofsky score ° °    
Medication ° ° ° °  
Vital signs ° ° ° °  
Laboratory examinations      
TSH, TT4, FT4, TT3, FT3 ° °    
Neuropsychological data      
Number connection test ° °    
RWT ° °    
SKT ° °    
HADS °     
SF36   ° ° °  
Other investigations      
Thyroid ultrasonography ° °    
Outcome (survival etc.) ° ° ° °  
  1. •: Scheduled at indicated EP.
  2. °: Scheduled after transfer to peripheral ward.