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Table 5 Schedule of evaluation points

From: The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome

 

EP 1.0

EP 1.1

EP 1.2

EP 1.3

EP 1.999

 

Screening

After 24 hours

After 72 hours

Weekly

After discharge

Screening

     

Inclusion and Exclusion criteria

•

•

   

Informed consent

  

°

°

°

Demography

     

Age, Gender

    

•

History

•

    

Laboratory examinations

     

TSH, TT4, FT4, TT3, FT3

 

•

•

•

 

rT3

  

•

  

Total protein, Albumin

 

•

•

•

 

BC, CRP, ATIII, Fibrinogen

 

•

•

•

 

Thyroid antibodies, T4/T3-Abs.

 

•

   

Other investigations

 

•

•

•

 

Temperature, Horowitz-Quotient

     

Vital signs

•

•

•

•

 

Evolution data

     

Medication

•

•

•

•

•

APACHE-II-/SAPS-II-Score, GCS

 

•

•

•

•

Diagnosis

 

•

  

•

HD/CVVH/CVVHDF

•

•

•

•

•

IABP

•

•

•

•

•

Persistent organ failure

    

•

Outcome (survival etc.)

    

•

 

EP 2.0

EP 2.1

EP 2.2

EP 2.3

 
 

After transfer to peripheral ward

After 3 months

After 6 months

After 1 year

 

History and clinical data

     

Burch-Wartofsky score

°

°

   

Medication

°

°

°

°

 

Vital signs

°

°

°

°

 

Laboratory examinations

     

TSH, TT4, FT4, TT3, FT3

°

°

   

Neuropsychological data

     

Number connection test

°

°

   

RWT

°

°

   

SKT

°

°

   

HADS

°

    

SF36

 

°

°

°

 

Other investigations

     

Thyroid ultrasonography

°

°

   

Outcome (survival etc.)

°

°

°

°

 
  1. •: Scheduled at indicated EP.
  2. °: Scheduled after transfer to peripheral ward.