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Table 4 Parameters for structure parameter inference [21]

From: The AQUA-FONTIS study: protocol of a multidisciplinary, cross-sectional and prospective longitudinal study for developing standardized diagnostics and classification of non-thyroidal illness syndrome

Symbol

Explanation

Value

αT

Dilution factor for T4 (reciprocal of apparent volume of distribution)

0,1 l-1

βT

Clearance exponent for T4

1,1 * 10-6 sec-1

DT

EC50 for TSH

2,75 mU/l

K41

Dissociation constant T4-TBG

2 * 1010 l/mol

K42

Dissociation constant T4-TBPA

2 * 108 l/mol

α 31

Dilution factor for T3

0,026 l-1

β 31

Clearance exponent for T3

8 * 10-6 sec-1

KM1

Dissociation constant of type-1-deiodinase

5 * 10-7 mol/l

K30

Dissociation constant T3-TBG

2 * 109 l/mol