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Table 3 Ghost erythrocyte membrane protein content and Na+K+-ATPase activity

From: Association between erythrocyte Na+K+-ATPase activity and some blood lipids in type 1 diabetic patients from Lagos, Nigeria

Parameter Control Type 1 diabetic patients
   A1 (n = 20) A2 (n = 14) A2 (n = 14)
Protein, μg/mL 5.4 ± 0.2 4.6 ± 0.4a 4.6 ± 0.3a 4.6 ± 0.4a
Total ATPase activity (micromole Pi/mg/h) 0.87 ± 0.05 0.42 ± 0.04ab 0.55 ± 0.07a 0.50 ± 0.09a
Digoxin sensitive Na+K+-ATPase activity (micromole Pi/mg/h) 0.59 ± 0.07 0.31 ± 0.04ab (52.5) 0.42 ± 0.07a (71.2)18.7 0.38 ± 0.08a (64.4)
Digoxin sensitivity, % 65.9 ± 0.05 75.6 ± 0.07a 74.3 ± 0.06a 75.1 ± 0.07a
  1. Data are expressed as mean ± SD and analyzed using Student's t-test (2-tail). Figures in parentheses represent Na+K+-ATPase activity in diabetic patients as a percentage of control. Figures in superscripts indicate percentage increase in Na+K+-ATPase activity in type 1 diabetics with glycemic control over those with poor glycemic control.
  2. Digoxin sensitivity is defined as percentage decrease in pump activity relative to undigoxinated enzyme,aP < 0.05 (Control vs. Type 1 diabetic patients), bP < 0.05 (A1 vs. A2). P < 0.05 was considered significant.