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Table 3 Ghost erythrocyte membrane protein content and Na+K+-ATPase activity

From: Association between erythrocyte Na+K+-ATPase activity and some blood lipids in type 1 diabetic patients from Lagos, Nigeria

Parameter

Control

Type 1 diabetic patients

  

A1 (n = 20)

A2 (n = 14)

A2 (n = 14)

Protein, μg/mL

5.4 ± 0.2

4.6 ± 0.4a

4.6 ± 0.3a

4.6 ± 0.4a

Total ATPase activity (micromole Pi/mg/h)

0.87 ± 0.05

0.42 ± 0.04ab

0.55 ± 0.07a

0.50 ± 0.09a

Digoxin sensitive Na+K+-ATPase activity (micromole Pi/mg/h)

0.59 ± 0.07

0.31 ± 0.04ab (52.5)

0.42 ± 0.07a (71.2)18.7

0.38 ± 0.08a (64.4)

‡Digoxin sensitivity, %

65.9 ± 0.05

75.6 ± 0.07a

74.3 ± 0.06a

75.1 ± 0.07a

  1. Data are expressed as mean ± SD and analyzed using Student's t-test (2-tail). Figures in parentheses represent Na+K+-ATPase activity in diabetic patients as a percentage of control. Figures in superscripts indicate percentage increase in Na+K+-ATPase activity in type 1 diabetics with glycemic control over those with poor glycemic control.
  2. ‡Digoxin sensitivity is defined as percentage decrease in pump activity relative to undigoxinated enzyme,aP < 0.05 (Control vs. Type 1 diabetic patients), bP < 0.05 (A1 vs. A2). P < 0.05 was considered significant.