Skip to main content

Table 3 Clinical data variance over time

From: Insulin versus oral agents in the management of Cystic Fibrosis Related Diabetes: a case based study

Variable Mean ± SD (Range) Insulin (n = 8) Sulfonylurea (n = 5) Metformin (n = 6) Thiazoli-dinediones (n = 6) P Value
ALT (U/L) Change/Yr 1.8 ± 3.0 (-2.0 – 7.8) 4.7 ± 8.6 (-2.5 – 19.0) -2.8 ± 22.0 (-41.5 – 26.5) -1.1 ± 7.7 (-11.0 – 9.5) (n = 5) 0.757
FEV1 (%) Change/Yr -0.3 ± 3.3 (-3.9 – 6.3) 1.4 ± 9.6 (-9.0 – 13.0) -1.2 ± 3.2 (-7.0 – 1.5) 5.2 ± 7.8 (-2.5 – 20.0) 0.422
Weight (kg) Change/Yr 1.5 ± 2.2 (-1.2 – 6.3) 0.5 ± 2.2 (-2.4 – 2.7) 1.8 ± 3.9 (-3.3 – 8.5) 4.3 ± 6.0 (0.3 – 16.0) 0.384
HbA1c Change/Yr -0.3 ± 0.2 (-0.5 – 0.1) -0.8 ± 0.7 (-1.8 – -0.1) -1.1 ± 1.4 (-3.2 – 0.6) -0.6 ± 1.3 (-3.2 – 0.5) 0.283
  1. SD, standard deviation; Yr, year; ALT, alanine aminotransferase; FEV1, forced expiratory volume at 1 second; HbA1c, percent glycosylated hemoglobin. P values for ALT and Weight are from one-way analysis of variance (ANOVA); P values for FEV1 and HbA1c are from Welch ANOVA for unequal group variances.